William Reed, appears as early as 1711 as an assemblyman signing a letter denouncing Cary’s Rebellion and in 1712, signing a letter petitioning help from the Governor of Virginia against the Tuscarora. In 1712, Reed was a member of the Virginia –North Carolina Boundary Line Commission. In 1715, Reed was named as vestryman for the Currituck Precinct parish. He became Proprietor’s deputy, a member of the Council and was acting Governor of North Carolina from 1722 to 1724. In 1723, he named himself and others as town commissioners to enlarge the town of Carteret, which was recently incorporated on the northeastern side of Roanoke Island. Reed died at his home in Pasquotank County.