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Material (1844-1891) including correspondence, account books, speeches, pamphlets, receipts, legal papers, and publications concerning William Robinson (an Irish immigrant) who was a newspaper publisher, town commissioner and mayor of Goldsboro, Wayne County, North Carolina, and his son Dr. Marius Emmet Robinson who practiced in Goldsboro, operated a drugstore with his brother, and was the first chief of staff of Goldsboro's first hospital.

Ten handwritten letters between William J. Blow and W. J. Marsh and handwritten transcriptions. This exchange of letters was about W. J. Marsh [or W. T. Marsh] "demanding satisfaction for offensive language used by Dr. Blow" towards him.

Papers of Willie Jordan Batts include medicinal drug recipes, typed transcription of the recipes, and "Dr. Willie Jordan Batts, Esq., Botanic Physician" by Hugh B. Johnston Jr.

The Van de Sande Family Papers include paper soldiers, horses, and weapons Thilleman van de Sande made circa 1775 in the netherlands; two diplomas for Thilleman; document about Thilleman becoming a doctor written by A. Ypey; and a diploma for Daniel van de Sande.

Papers (1783–1930, [bulk 1862–1930]) consisting of correspondence, diaries, photographs, photograph albums, literary manuscripts, newspapers and newspaper clipping, a book of poetry, genealogical notes, etc., documenting the life of Commodore George L. Dyer, whose naval career spanned the years 1870 to 1908, and his family. He served in various stations, with particular emphasis on the West Indies, the Asiatic Station, Cuba, Madrid (as naval attache), and Guam (as governor).

This ledger (1886-1903) contains accounts for a general store in Bethel, N.C., owned by Guilford Andrews, one of the town commissioners who incorporated Bethel in 1873. Loose papers (mostly concerning Guilford Andrews in Pitt County) found in the ledger are land records (1879-1887), insurance policies (1875, 1882), tax receipts (1880-1898), receipts and bills of lading (1880-1884, 1900), a license to sell liquor (1877), business correspondence (1884) and accounts.

This collection (1980s-2010s) contains material related to the life of Michael J. Hamer, an English professor at East Carolina University in Greenville, North Carolina, from 1986 through 2013, and a prolific songwriter, singer, and band leader who died in 2017. Included are notebooks containing his handwritten lyrics, poems, photographs, reel to reel tapes, clippings, and other material pertaining to his musical career.

Original and typescript copy of "A Nurse's Education", notes by Mattie Shackleford while at Norfolk Protestant Hospital.

Ledger belonging to Dr. George Kirkman and Dr. Daniel Brower.

Records (1955-1994, undated) of architectural firm, Dudley & Shoe Architecture, Greenville, NC. Contains 376 items including blueprints, photos, images, and other documents developed by the firms founders.

Biographical account (10/19/2002) of Paul E. Carrigan and the aerological personnel who served in U. S. Navy Fleet Air Wing Four, Territory of Alaska, 1942-1945, by Willard G. Burris, including photocopies of documents, newsletters, photographs and

Collection includes papers related to the personal life and non-university activities of East Carolina University History Professor Lawrence Fay Brewster (ECU professor from 1945 to 1969) for whom the Lawrence F. Brewster Classroom Building on campus was named in 1974. Included are materials (1857-1945) related to his parents and ancestors, Brewster's early life and education through earning his Ph.D., his teaching job at Cranleigh School for Boys in St. Petersburg, Florida, and his work with the Works Progress Administration as Research Editor for the Historical Records Survey of North Carolina. The vast majority (1960-1991) of the collection concerns his work as historiographer for the Episcopal Diocese of East Carolina and writing his "History of the Protestant Episcopal, The Diocese of East Carolina."

The collection contains the papers of Lavinia "Venie" Roberts (1833-1923), a native of New Bern, North Carolina who wrote an unpublished memoir of her experience during the Civil War. In addition to the memoir, the collection includes material documenting the history of New Bern, the life of wealthy white Southerners during the Antebellum and Reconstruction periods, the lives of those enslaved from the point of view of their enslavers, the efforts of the United Daughters of the Confederacy in New Bern, and genealogical material related to the Cole and Roberts family.

The collection includes papers and publications produced or related to the administration of John Decatur Messick. Materials include biographical records, correspondence, articles, newspaper clippings, administrative records, and other miscellaneous items.

Files (1717-1957) of Murfreesboro, N.C. lawyers and Hertford County, N.C. officals, including correspondence, legal files, reports, financial records, etc. of B.B. Winborne, Attorney at Law, Winborne & Lawrence, Winborne and Winborne, Lemuel R. Jernigan and James L. Anderson.