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The Nell Wise Wechter Papers contains copies of the author's books, Taffy of Torpedo Junction (1957), Betsy Dowdy's Ride (1960), Swamp Girl (1971), and The Mighty Midgetts of Chicamacomico (1974). Also included are the typed and written drafts, typed manuscripts with revisions, original manuscripts, and galley proofs for her books. There is also correspondence from the Library of Congress, British Embassy, and Mariners Museum regarding Wechter's requests for information to assist her in writing her novels.

Collection (1939) consisting of a pamphlet entitled Bishop[Thomas Campbell] Darst and East Carolina during the past twenty five years [1914-1939]. by Frederick Arthur Turner.

This collection contains materials related to an assignment, "Draw History and Draw the Course", that Dr. Kenneth Wilburn used in many of his courses from 1984 to 2014.

Papers (1792-1969) including correspondence, financial papers,a diary, a cipher book, newspaper clipping, and a family history references to school, comments on Democratic Party, genealogical material, etc., related to the Sills family residing at Belford Plantation in Nash County, North Carolina.

This collection contains copies of the ECU Medical Review and later iterations of the publication.

Papers (1853-1937, undated) consisting of correspondence, financial and legal papers, letters, records of insurance, papers on business and farming, genealogical records, etc.

Papers (1857-1887) including patients accounts, medications, hired help accounts, and records of merchandise bought and sold.

Minutes, programs, correspondence, journals, reprints, reports, posters, and miscellaneous records (1902-2016) documenting the North Carolina Academy of Science.

Papers (1766-1898, undated) of the Clark and Spragins families of Halifax County, Virginia, including correspondence, financial records, legal papers, political reference, and miscellaneous.

Collection contains mainly material related to the African American Navy Band members who served at the Great Lakes Naval Base during World War II (1942-1945). This material includes programs and related material from the February 28-March 2, 2003, salute to these African American band members that was held in Chicago, Illinois, and from former band member Carl Foster's participation in a symposium sponsored by the North Carolina Museum of History in 2003. Other material includes programs (1987) for concerts by the North Carolina Jazz Ensemble and a 1945 USO Hawaii booklet. A second focus of this collection is on the lives of Alex Albright's family members including uncles on his mother's side and their involvement with the CCC (Civilian Conservation Corps) and World War II service and death.

This collection of Tom Shields' records contains correspondence, administrative files from East Carolina University's Roanoke Colonies Research Office, his publications, event announcements and brochures, press releases, photographs, audio cassettes, and digital media on floppy and zip disks.

Scrapbooks (1934-1954) containing correspondence, clippings, photographs, programs, and other material related to Lewis S. Bullock's work developing and conducting community choruses formed in rural Eastern North Carolina towns in the 1930s, the Eastern Carolina Symphonic Choral Association, the North Carolina Symphonic Choir, the International Male Chorus in the U.S. Army during World War II and the American Male Chorus which was formed after the war ended and finally disbanded in 1954.

Papers (1830-1947) consisting of correspondence, legal documents, newspaper clippings, photographs, letters regarding common disease and miscellaneous.

This collection contains the records of the Friends of Portsmouth Island including minutes (1990-2016), correspondence, by-laws, 1994 incorporation documents, grant documents, and issues (1991-2016) of their newsletter Doctor's Creek Journal. Also included are documents related to Homecomings at Portsmouth Village (1980, 1992-2016), a DVD produced by the National Geographic Society titled "Portsmouth: Island with a Soul," and a DVD of a project done by UNC-Chapel Hill students titled "Portsmouth—In Search of the Past."