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The collection contains papers related to Dr. Mabe's personal medical practice, personal papers, product advertisements, and journal.

Records (1872-1892) including correspondence, minute book, ledger, social organizations, fraternal organizations, debts and credits, dues, taxes, fines, and miscellaneous.

The papers track the history and development of Pitt County Memorial Hospital(previously Vidant, now ECU Health) and Brody School of Medicine, including scrapbooks, photographs, publications, and videos.

This collection (1823-1999) contains the papers of Robert "Bob" Boyd Robinson III. Robinson, born in 1948 in Halifax County, N.C., was a member of various groups including the Sons of the Revolution in the State of North Carolina. His papers include materials related to various families of Northeastern North Carolina and Southeastern Virginia.

Willard and Daisy Rowe Papers (1963-2006) contain newsletters,clippings, publications and a poster documenting the work of the Evangelical Baptist Mission in Franklin County, North Carolina, and in Guatemala.

This City of Washington Statistical Map No. 1 showing the Valuation of Real Property as determined by the assessment of 1878, and corrected to July 1st, 1879, was compiled by Lieut. F. V. Greene, U.S. Eng'rs, Ass't to Eng'r. Comm'r. to accompany the annual report of the Commissioners of the District of Columbia, for the year ending June 30th, 1880.

Letter (June 22–23, 1840) from John and M. J. Atkins of Averasboro, North Carolina, to their cousin Caroline E. Turner in Montgomery, Alabama. The writers discuss family news, domestic activities such as dressmaking and preserving, local economic "hard times," and mention a forthcoming Whig political meeting in Averasboro.

Papers (1933-1973) of U. S. Marine Corps aviation officer (Major Gen.) who served in World War II, Korea, and Vietnam, and who retired as commander of the Cherry Point, NC Marine Air Station, including correspondence, reports, war diaries, citations, certificates, and military records. See also related Oral History #30.

Papers (1887-1933) including diaries, medical school notes, school register, ledger, daybooks, memo books, clippings, physician's birth record stub book, a funeral memorial record, a photograph and miscellany.

Collection (1973–1989) of color slides documenting J. Y. Joyner Library at East Carolina University, in October 1973, prior to the construction of two extra floors and the addition of a new west wing to the building, for Library Science 1000 class; also photocopies of correspondence, historical research reports, and newspaper clippings about the Greenville Town Common Confederate flags controversy, in 1983–1989; also photocopies of newspaper clippings about the Confederate flag, 1983–1989. Collection also contains 4 photographs of individuals from the Collins-Becton family.

Muster roll for a detachment of the 29th Regiment U. S. Colored Troops Detachment under the command of Capt. Wilson Camp, dated June 30 – August 31, 1865. The roll documents the names, ranks, enlistment data, and service records of the 17-man detachment consisting of soldiers from Illinois, Indiana, and Maryland.

A typescript of "Three years, three months and nine days", a memoir of a U.S. Navy enlisted man as a Japanese POW. (undated)

The Edsall R. Johnston, Jr., Papers consists of materials pertaining to the USS Mount Olympus (AGC-8), including a European cruise journal (1952) and materials pertaining to the U.S. Naval Training Center in Bainbridge, Maryland. All materials are photocopies.

Genealogical materials for Dixon, Haddock, Hemby, Laughinghouse, Nelson, Jenkins, Baldree, Dail-Deal, Flake, Kittrell and other families of Pitt County, NC. Also includes local history and biographical sketches by William B. Kittrell, a DVD of a Motion picture of Greenville, North Carolina (ca. 1940s-1950s) showing ordinary daily scenes and local buildings, CD of early 20th Century Pitt County schools, and 2 DVDRs made from 8mm reels of home movies (1947-1967) made by the Keel family of Greenville, N.C.

This collection contains a seventeen-page letter from medical missionary Herbert P. Ramsey writing from Soochow, China, in 1924 about his experiences as surgeon at Soochow Hospital. Also included is a letter written in 1927 by his brother William H. Ramsey describing the recent escape of Herbert Ramsey and his family from Soochow in the face of anti-Western instigators.