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The collection includes various aspects of public health in North Carolina beginning in the early 20th century.

Papers (1967-1980) including correspondence, memoranda, minutes, reports, bills, clippings, photographs, letters, etc.

Papers (1907-1968) documenting the U.S. Naval career (1910-1946) of Admiral Jules James consisting of correspondence of Naval travels, logbook, diaries, newspapers clippings, radio press news.

Collection (1903-2004) of materials relating to Wilbur and Orville Wright and the origin and development of flight in Italy, especially the Wright Brothers activities in Italy (1909-1910), acquired from the Gianni Caproni Museum, at Trento, Italy. Included are photographic and printed materials, stamps, videocassettes, and original art, assembled for a temporary exhibit for the centennial of the first flight at the Wright Brothers National Memorial, 13-17 December 2003.

The collection consists of reports, publications, advertising materials, and photographs used and/or created by the ECU College of Nursing.

This collection includes records related to the Croom Family especially the annual Croom Family Reunion held at the Croom Meeting House at Sandy Bottom Community on Highway 55 West in Lenoir County, North Carolina. Included are a 1930 photograph of the first Croom Family Reunion, programs, attendance sheets, minutes, obituaries, updated family charts, articles about the Reunion, and tombstone listings.

John L. Porter's notebook (Pensacola, Fla., 1860), blueprint, photocopies of blueprints, newspaper clippings and photographic print, relating to U.S. Navy ship construction and C.S. ship construction, including drawings of CSS Virginia (USS Merrimac) and other ships; Porter family genealogy, ca. 1860-1936.

The largest portion (1911-1947) of this collection (1837-1993) contains correspondence, photographs, publications and ephemera related to the extensive charitable interests of Mary Estelle Crawford Fry, her husband James Woods Fry and son Gilbert Crawford Fry, all of Philadelphia, Pennsylvania. The charities include the Bethel Mission operating out of Hong Kong at the time of this correspondence (1938) due to war in China, the San Miao Orphanage in Saratsi (Suiyuan Province) of Northern China [later became part of Nei (Inner) Mongolia], the China International Famine Relief Commission, missions dealing with French and Belgian orphans of WWI, and the International Students' House conducted by the Christian Assoc. of the University of Pennsylvania. Earlier correspondence (1837-1869), unrelated to the above mentioned charities, is mainly written between Mrs. Mary M. Crawford of Boston, MA, Mrs. Addie A. Stien of Norristown, PA, and Sower family members in Boston and Norristown. Also included are family photographs and family history information related to the Chitty, Stroup (Strup, Strupe, Strub), and Ruede families of Forsyth Co., NC.

Papers (1961-2007) of the Halifax County Historical Association (N.C.) including correspondence of general nature concerned with group tours, bibliography sketch, financial records, membership rolls, itineraries etc. Various historical documents, photographs, ephemera and clippings relate to the history of Halifax County including Rosenwald schools and Brick School among many other topics (1816-2011). Other items (1972-2011) such as manuscripts, printed materials, digital materials, and a video recording concern the work of Maxville Burt Williams, a social studies teacher, principal, author and playwright and his works relating to the history of Halifax County, North Carolina, including First For Freedom a play about the Halifax Resolves of 1776; The Struggle, a play about Halifax County during the American Revolution; and The Schroonchers, a play about Eastern North Carolina in the summer of 1948.

Papers (ca. 1878-1980) including manuscripts, notes, ledgers, clippings, photographs, printed forms and published works, pertaining to the life of Bertie County, N.C., native Rev. Jesse W. Castelloe and his family.

Booklets from the Health Heroes series.

Papers (1943-1945) consisting of photocopies, letters, biography, cruise history, map and commissioning papers.

Papers (1845-1859, 1876, undated) including shipping records, bills of lading, promissory notes, receipts, indentures and correspondence.

Records (1899-2006, undated) of Pt. Pleasant, West Virginia shipbuilding company, including engineering drawings, blueprints, photographs, and negatives, correspondence, contracts, reports, personnel files. Production files, etc.