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Collection (1762-1894) including correspondence, deeds, accounts, receipts, promissory notes, plat, church minutes, judgment, etc. of early settlers of Poplar Grove Plantation, Scott's Hill, N.C.

Papers (1845-1992, undated) including correspondence, genealogical information, photographs, a water color, clippings, a doctor's journal, a recipe book and miscellaneous.

This collection contains material (1735-2004) detailing the history of the A.C. Monk Tobacco Company and the Monk Family of Farmville, Pitt County, North Carolina, including financial records, correspondence, tax documents, audit reports, wills, estate records, stock certificates, deeds, receipts, ledger, press releases, portfolios, and blueprints, land records, clippings, publications and broadsides, and family histories and Farmville histories. Also included are photographs (daguerreotypes, ambrotypes, tintypes, cartes de visite, negatives, 35 mm prints, large framed images), and charcoal portraits, of Monk, Quinerly, Turnage, and May family members of Farmville, North Carolina.

Papers (1947-1960) including correspondence, references concern Bible, auditing of books, school events, receipts, pilgrims, and miscellaneous.

Papers (1930–1963) including correspondence, military orders, engineering notes, weather, handbooks, diaries, reports, newsletters, programs, photographs, clippings, citations, certificates and miscellany.

Collection (1799-1897, 1913) including correspondence, 1835-1897, 1913, and financial records, 1799-1894, of New Bern, NC merchant, whose store was used by Union troops, and who was appointed "Superintendent of Poor Whites" for Craven County, NC.

Records (1936-2024) including correspondence, historical writings, letterhead, address lists, membership applications with supporting documents, minutes, financial records, brochures, pamphlets, periodicals and yearbooks of the North Carolina Chapter and The Gazette of the General Society of Colonial Wars, the Society of the Daughters of Colonial Wars in the State of North Carolina yearbooks and the by-laws and yearbooks of the General Society of Colonial Wars.

Papers (1940–1945) of a U.S. Naval Reserve medical officer, including scrapbook of clippings, photographs, correspondence, photographs, original art, and memorabilia compiled while serving in the U.S. Naval Reserve at the Toledo, Ohio naval recruiting station, 1942–1943; And letters sent to his parents Dr. and Mrs. Carroll C. English, in Louisville, Kentucky, while serving aboard USS Trathen (DD-530), 4 April 1943–5 December 1944

The Karel B. Absolon Collection is comprised of Absolon family papers and Karel B. Absolon's research and collecting interest, particularly Theodor Billroth. The papers relating to Absolon's family span three generations and include Karel B. Absolon, Karel Absolon, Willibald Absolon, and Jaroslav Bakes (a cousin to Karel Absolon). Karel B. Absolon's primary research interest was Austrian abdominal surgeon Theodor Billroth (1829-1894). Absolon also collected items related to European, primarily men, in the science field. The collection includes correspondence, translations, prints, photographs, articles, ephemera, and original documents.

This collection contains literary and personal papers of Dr. Peter L. Makuck, Distinguished Professor Emeritus of the English Department, East Carolina University, Greenville, North Carolina, where he taught from 1978 to 2006. Included are correspondence, lecture and teaching notes, and drafts of poems and short stories. A large portion of this collection pertains to the publication Tar River Poetry from its founding in 1978 by Dr. Makuck, as a publication of the English Department at ECU, until 2015. Included are correspondence and all but one of the issues.

Papers (ca. 1923-1978, undated [bulk: 1955-1975]) of a prominent Greenville, North Carolina attorney and Democratic Party activist, who served as administrative assistant to U. S. Senator Samuel J. Ervin, Jr., 1955-1975, notably during the Watergate Scandal, and including personal, social, business and political files, photographic prints, and oversized materials relating to his life in Washington, DC, and North Carolina. Also contains information related to the life of his wife Marie Hardee Spain, a Greenville, North Carolina, native.

This collection contains letters (1964-1967) written by brothers Terrence and Dennis Miller of St. Louis, Missouri, who joined the U.S. Army during the Vietnam War. Letters written by Dennis Miller during 1967 document his time serving in Vietnam as part of 3rd BN, 60th Ord Co. Also included are letters written by fellow soldiers and friends (through 1971), service records, negatives, military payment certificates, and Vietnamese money.

Papers (1751-1816) including correspondence, estates records, wills, deeds and indentures, accounts and other financial papers.

Files (1969-1994) belonging to retired ECU Biology professor Dr. Vincent J. Bellis pertaining to the environmental impact of the Chicod Creek (North Carolina) channelization, the East Carolina University Institute for Coastal and Marine Resources, North Carolina Academy of Science, and material concerning the Sierra Club of NC and other environmental groups. Included are correspondence, affidavits, reports, notes, conference proceedings, environmental studies, and newsletters.

Collection (1841-1968) including correspondence, legal papers, accounts, receipts, pamphlets, clippings, photographs, poems, pocket ledgers, Civil War correspondence, letters and miscellaneous.