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The collection consists primarily of photographic, blueprint, journals, class photos, and other advertising materials used and/or created by the Medical News & Information department of East Carolina University.

Collection consists of a two volumes titled "Journal of a Cruise from Norfolk, Virginia to the Pacific Ocean in the United States Frigate United States, Isaac Hull, Esq'r, Commander" kept by Philadelphian midshipman Lawrence Penington from 4 December 1823, through 22 April 1827. United States was one of six frigates authorized to be constructed by the Naval Act of 1794 and it served as the flagship for Commodore Hull who was head of the American naval squadron on the Pacific Coast of South America. Penington documents navigation statistics, weather reports and daily ship life, along with the larger issues of interaction between the American naval squadron and British, Spanish, Chilean, Colombian and Peruvian naval and military counterparts.

This collection is the account book for Dr. Robert H. Wyche between 1865 and 1869.

Collection (1889-1890, 1893-1894) including Civil War black soldiers pension and compensation applications compiled by Frederick C. Douglass, a black lawyer, minister, and teacher in New Bern, NC who served as a government pension agent, 1889-1897.

Genealogical materials for Dixon, Haddock, Hemby, Laughinghouse, Nelson, Jenkins, Baldree, Dail-Deal, Flake, Kittrell and other families of Pitt County, NC. Also includes local history and biographical sketches by William B. Kittrell, a DVD of a Motion picture of Greenville, North Carolina (ca. 1940s-1950s) showing ordinary daily scenes and local buildings, CD of early 20th Century Pitt County schools, and 2 DVDRs made from 8mm reels of home movies (1947-1967) made by the Keel family of Greenville, N.C.

Papers (1938–1993 [Bulk: 1938–1953]), of U.S. Naval Reserve officer and destroyer escort commander, including official files and service records, and a History of USS SC-631; postwar correspondence relating to the Destroyer Escort Commanders Organization (DECO); a History of the USS Kendall C. Campbell (DE-443), by Cdr. Richard E. Warner; a scrapbook, compiled by Cdr. Warner's father, entitled Sub Chaser Navy: World War II, which documented the achievements of destroyer escorts, and Warner's service in destroyer escorts, patrol craft, and sub-chasers; also oversize material including a blueprint of USS PC-497 [renamed SC-497]; and a laminated fact sheet entitled United States Ship USS Kendall C. Campbell (DE-443) including orders, letters, printed forms, certificates, commissions, and documents signed by Admiral Chester Nimitz; Secretaries of the Navy Frank Knox, Francis P. Matthews, Claude A. Swanson, and James Forrestal; by Governor of California Frank F. Merriam.

Collection (1760-1965) consisting of financial and legal documents, correspondence, genealogical material, a scrapbook, newspapers clippings, photographs, reports.

Peart's Journal : Prepared from notes kept on a prisoner of War odyssey from Bilibid Prison, Manila, P.I., to Manchukuo, via the prison ship S.S. Oryoku Maru (undated)

Records (1948-1972) of Wilson, NC tobacco warehouse, including poundage sheets, sales records, ledger sheets, daily summary journals, correction sheets, and other financial records.

Material (1844-1891) including correspondence, account books, speeches, pamphlets, receipts, legal papers, and publications concerning William Robinson (an Irish immigrant) who was a newspaper publisher, town commissioner and mayor of Goldsboro, Wayne County, North Carolina, and his son Dr. Marius Emmet Robinson who practiced in Goldsboro, operated a drugstore with his brother, and was the first chief of staff of Goldsboro's first hospital.

This notebook is an 1870 student's notebook containing field notes of a Survey of the Coast of North Carolina done for the United States Coast Survey. It was likely kept by Jacob Bell Cornell (1848-1897), a member of the Class of 1872 at Rutgers College in New Brunswick, New Jersey. Of specific interest are a diagram and calculations associated with a lighthouse in the Pamlico Sound and references to Portsmouth Island and Swan Quarter.

Private journals/ships' logs (October 1860 - July 1878) of Benjamin Thompson, master of the brigs Progressive Age and T. A. Darrell, and the ships Sportsman, and Harrisburg (v. 1, 1860-1865), commander of the ship Columbia (v. 2, 1865-1870), master of the ship Peruvian (v. 3, 1870-1872), and captain of the clipper ship Great Admiral (v. 4, 1874-1878), illustrating his career aboard sailing ships trading between England, the east and west coasts of America, Southeast Asia (Singapore, Manila, and Hong Kong), and Tokyo, Japan, including highly detailed and dramatic accounts of shipboard life and commercial operations.

Papers (1882-1954, undated [bulk 1882-1920]) of U. S. Navy surgeon, including correspondence, reports, and miscellany.

This collection contains a diary (February 16, 1863-May 16, 1863) and correspondence (September 14, 1862-September 15, 1864) written by an unknown private serving in Co. I of the 44th Massachusetts Volunteers Regiment during the Civil War. The diary was written by a man named Daniel while his company is camped at Brice's Creek, North Carolina. The letters cover a longer span and are written by Daniel to his sister Susie. During that time, his company was camped at Readville, Newberne (now New Bern) and Brice's Creek in North Carolina, near Fort Smith and at Arlington Heights in Virginia, and finally at Fort Delaware in Delaware.

Scrapbook, clippings, correspondence, photographs, reports, and other materials related to the World War II career of Lt. Commander Richard Hamilton Smith aboard the USS Teak and the USS Thomas J. Gray, and especially related to the successful evacuation during 7-9 September 1945 of British, Australian and American prisoners of war held by the Japanese at Kiirun, Formosa [Taiwan].