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Broadside announcing the "Fugitive Slave Bill" of 1850. Passed by the Senate and House of Representatives and signed into law by President Millard Fillmore, the "Fugitive Slave Act" gave enslavers greater power in capturing freedom seekers, even those who had fled to free states.

Collection (1872-1930, undated) relating to the medical practice of Dr. D. DeForest Douglass, Springfield, MA, 1872-1905, consisting of correspondence, financial papers, development of artificial limb fitting, receipts, mortgages, plat of land.

Papers (1873, 1892-2009, undated) concerning Littleton Female College (later called Littleton College) in Warren County, North Carolina, and its alumnae include correspondence, programs, college history, alumnae lists, clippings, pamphlets and speeches, etc. The college opened in 1882 and closed after a disastrous fire in 1919. The Littleton College Memorial Association was founded in 1926.

Includes a complete set of the monthly periodical, The Medical World, for the year 1908.

Papers (1907–2001) of Lt. Cmndr. John W. Gilpin, U.S. Navy, including materials relating to his family; attendance at the U.S. Naval Academy (Class of 1941); World War II service on the destroyers USS Monaghan, USS Trathen, and USS Evans; his postwar education, business career, and fraternal life.

Collection (1965-1979) consisting of correspondence, foundations minutes, biographical manuscripts, letters.

Papers (1792-1969) including correspondence, financial papers,a diary, a cipher book, newspaper clipping, and a family history references to school, comments on Democratic Party, genealogical material, etc., related to the Sills family residing at Belford Plantation in Nash County, North Carolina.

Papers (1851-1887) consisting of a memoir, correspondence, legal papers, transcripts, military documents, genealogical materials, and photographic scans pertaining to William Henry von Eberstein (1821- ca. 1890). Descending from German and English aristocracy, he was born in St. Servan, France, and also lived on the Isle of Guernsey before becoming a mariner at age 13. A mariner, soldier, and farmer, von Eberstein moved to Chocowinity, Beaufort County, North Carolina, in 1851 and established himself in business. Later he captained various ships out of Washington, North Carolina, and served in the Confederate army.

The collection consists of photographs, diplomas and other educational records, correspondence, artifacts, and ephemera from Clara G. Gentry, a registered nurse.

Papers (1931-1935) including correspondence, reports, photo albums, missionary work, etc.