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The Louis Orr Collection contains a set of forty-eight prints of the original fifty-one print set (and one replacement print) made from etchings of North Carolina historical landmarks and architectural sites. The etchings were created from 1939 to 1952 by artist Louis Orr, a world-renown etcher, at the behest of North Carolina resident Robert Lee Humber who wanted to preserve North Carolina's heritage by providing the artwork to schools, colleges, public libraries and institutions throughout the state.

This collection contains histories of Webb's Chapel United Methodist Church in Lenoir County, North Carolina.

The Richland County Ballot (1876) is a "tissue ballot" that was used in the South Carolina "White Supremacy Election."

Papers (1926-2003) covering the schooling and naval service of U. S. naval officer, USNA class of 1931, Captain James H. Brown, including correspondence, reports, publications, clippings, and photographs. Extensive material pertains to his service during World War II aboard the USS SHAW (1940-1942), USS ABNER READ (1942-1944), and the USS AMMEN (1944-1945), as well as his service before and after World War II.

Papers (1978-2014) of Inez Fridley, Greenville City Council Member, Mayor Pro-Term, and advocate for preserving nature in the urban environment. Includes files reflecting her concern for planning and zoning, as a founding member of Tar River Neighborhood Association (TRNA), a member of Tar River/University Neighborhood Association (TRUNA), and as a member of the Rotary Club.

Glenn Charles Ames, born 29 March 1913 in Wisconsin, served the US Military from 1935-1975, primarily in the National Guard. The Glenn C. Ames collection spans the years 1927-1986 and consists of 598 items, including manuscripts, printed materials, and photographic prints relating primarily to his service in the 41st Infantry Division, United States Army, during World War II. The collection also documents his service as commanding general of the California National Guard, 1967-1975.

John L. Wooten's daily physician log from 1962.

Record volumes (1877-1987, undated) including Great Swamp Primitive Baptist Church Record, 1884-1980; Record of Primitive Baptist Church at Great Swamp, 1877-1915; [Great Swamp Church] Members / Conferences, 1916-1930; and loose material removed from Garner Family Bible including letters, clippings, emphemera, and Garner family genealogical information, ca. 1878-1987, undated

Slides, posters, photographs, publications, and other memorablia of Dr. William H. Waugh.

Collection (1934-2025, undated) of programs, constitutions, bulletins, reports, membership records, memorials, correspondence, scrapbooks and clippings related to the Delta Kappa Gamma Society International and its Beta Alpha and Delta Chapters in Greenville, North Carolina, and Sigma Chapter in Kinston and Lenoir County, North Carolina.

Papers (1953-1991) of USAR officer, system engineer, and senior logistics analyst, including correspondence, a diary (1969-1976), photo albums, clippings, and miscellaneous materials.

This collection includes 108 Chatham County, North Carolina, warrants (1804-1840); 2 Onslow County, North Carolina, grants (1788, no date); and 1897 financial receipt with 4 handwritten medicinal cures by Wyley M. Cates of Teer and Alamance County, NC, and print ads for his cures.

Vaughan Family Papers (1872-1900, 1969, undated) includes photograph albums containing images of family members from Hertford County, North Carolina. Also included is Uriah Vaughan correspondence (1876-1887) and a photocopy of the 1969 appraisal of Uriah Vaughan Heirs Property in Murfreesboro, North Carolina.

Papers (1888-1899) including North Carolina school register for a Halifax County School, 1888-1899.

The papers track the history and development of Pitt County Memorial Hospital(previously Vidant, now ECU Health) and Brody School of Medicine, including scrapbooks, photographs, publications, and videos.