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William "Bill" Cain papers contain materials from his career at ECU and personal items.

U.S. Navy Memorial Foundation Collection: Arch F. Seabrook Papers consists of one photograph that features the officers of USS Liddle (APD-60) in the Leyte Gulf.

Artwork and prints, primarily oversized, found in Country Doctor Museum items. Includes prints from "A History of Pharmacy in Pictures," "A History of Medicine in Pictures," "History of Anesthesia in Pictures," "Gay Philosopher" by Henry Major, "Pioneers of American Medicine" by Dean Cornwell, and other prints.

F.W. Fisher's ledger 1901- 1909 of receipts, expenses, dues, and officer's reports of King's David Lodge No. 24 Ancient Free and Accepted Masons, Kinston, Lenoir County, North Carolina, United States. Anonymous Donor.

Papers (1883-1964) of the noted author Inglis Clark Fletcher of historical novels set during the 17th and 18th century in colonial North Carolina.

This collection contains two photographs of the internationally recognized conjoined twin brothers, Chang and Eng Bunker.

Papers (1876-1881) including correspondence, calling card, an invitation, letters.

127 World War II era photographs depicting members of the United States Marine Corps. African American servicemembers in photographs are assumed to be members of the 51st Defense Battalion, commonly refered to as the Montford Point Marines, the first African American unit in the Marine Corp. Also included in the collection are photographs of white Marine Corps members as well as a number of unidentified personal photographs, many of which depict African American women and children.

Major General Charles Justin Bailey was born at Tamaqua, Pennsylvania, on June 21, 1859. He commanded the 81st Infantry Division, American Expeditionary Forces, fighting in France during 1918 and 1919. Bailey compiled this album during 1918 and 1919 and it contains postcards of French and German towns and provinces; a few letters; photographs of France and the 81st Division including behind the lines scenes, Camp Jackson in Columbia, South Carolina, and identified officers and dignitaries; clippings and ephemera; and eight large color fold-out maps. The strength of the collection is its representation of World War I in France.

Records (1937-1960) including correspondence, work orders, product invoices, requisitions, receipts, advertisements, photographs, and publications.

This collection contains a single photograph album that highlights the Sandhills region in North Carolina from 1914 to 1921.

Papers of Paul Green (1985) documenting the life and literary career of the noted Lillington, North Carolina-born American novelist and playwright whose works focus on North Carolina folklore and themes, consisting of incomplete sample proof pages of the first few pages of his dictionary of Cape Fear language and slang, entitled Cape Fear Valley People: A – B, covers, p. 1,4-6, by Paul Green; edited by Rhoda H. Wynn (1985) and transmittal note (16 March 1985) from Heritage Printers, Inc., Charlotte, NC, relating to possible publication; the text later appears in Paul Green's Wordbook: An Alphabet of Reminiscence, by Paul Green; edited by Rhoda H. Wynn; Foreword by John M. Ehle (Boone: Appalachian Consortium Press; Chapel Hill, N.C.: Paul Green Foundation, 1990) 2 vols.

This collection contains a items related to student life and academics at East Carolina including certificates, event programs, brochures, and memorabilia.

ECU's Joyner Library was awarded a 2020 Library Services and Technology Act (LSTA) Community Connections grant through the State Library of North Carolina. The theme was "She Changed the World: North Carolina Women Breaking Barriers" in honor of the anniversary of the ratification of the 19th amendment. This award is for projects "that advance excellence and promote equity by strengthening capacity, expanding access, and community engagement in North Carolina's libraries."