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This collection contains financial records (including also bills of sale for enslaved persons) and deeds (1743-1872), and correspondence (1821-1891) related especially to Elias Fort and Dr. Matthew C. Whitaker of Halifax County, N.C. The correspondence also concerns other members of the Whitaker family and related families.

Collection (1761-1966, undated) consisting correspondence, financial papers, shipping records, land records, printed material, receipts, shipping records, etc.

Collection (1902-2003) of genealogical and historical research files compiled by John Henry Oden III. Also includes the R. C. Chadwick Mercantile Records, Claude F. Pilley Papers, and the Windley Family Papers. Consists mostly of copies of wills, tax records, letters, deeds, newspapers, birth certificates, family trees, and photographs related to families in Beaufort, Washington, Hyde, and Halifax counties, N.C.

Diaries, journals and letters (1897-1906, 1986-1988) of Mormon missionaries in Eastern North Carolina (1897-1906), including William A. Adams, 1900-1902, James Godfrey, 1899-1901, William M. Hansen, 1897-1898, William R. Hobbs, 1901-1903, Lewis Johnson, 1903-1905, William A. Petty, 1905-1906, and James Taylor, 1900-1902, along with Memoirs, Notes, clippings, anecdotes and other materials compiled by Joel Grant Handcock, for use in the book Strengthened by the Storm.

Papers (1922-1936) consisting of correspondence, conference reports, clippings, pamphlets, information of climate season, Christians celebrations and magazine articles.

The collection includes various aspects of public health in North Carolina beginning in the early 20th century.

Papers (1870-1950, undated) of clerk of Pitt County Superior Court and his sons, consisting of correspondence, land records, legal records, pamphlets, reports, essay, poems, receipts, speeches, ledger books, and miscellaneous.

Documents and printed materials relating to Greenville, NC including high school and college programs, postcards, World War II ration books, etc. Also, genealogical correspondence, notes and research files pertaining to the Davenport, Flanagan, Neville, and related families of Pitt, Edgecombe, Halifax, and Nash counties, North Carolina.

Documents pertaining to World War II activities of a squadron designated at various times as Bombing Squadron 106 (1943-1944), Patrol Bombing Squadron 106 (1944-1945), and Patrol Squadron 106 (1945-1946), including historical summaries, action reports, war diaries, interviews operational orders, articles, rosters, etc.

Papers of Cleanth Brooks (1951-1986) documenting the life and literary career of the noted Murray, Kentucky-born American editor, literary critic and educator at Yale University, who was influential in the New Criticism movement as editor of The Southern Review, 1935-1942; consisting of loose manuscript items transferred from the Stuart Wright Book Collection, including Brooks' signed contract to sell his books and literary periodicals to Stuart Wright correspondence between Brooks, George Garrett Stuart Wright; also a reprint of Milton and the New Criticism, by Cleanth Brooks (1951).

Papers (1930-1949) including correspondence; agriculture and gardening; export of flowers and vegetables; travel account; letters and miscellaneous.

This collection contains documents (1821-1994, bulk 1860s-1910s) related to the Newsom family, especially Marion Eaton Newsom, of Littleton, Warren and Halifax Counties, North Carolina. Included are correspondence, land records, legal records, financial papers, and a family history written by Marion E. Newsom (1909, addendum 1911) about the Newsom and Nicholson families. Some material also relates to the Whitaker and Heptinstall families. A large part of this collection also documents the history of Littleton and institutions there such as schools, churches, and Littleton Female College.

Papers (1772-1861) including financial records, correspondence, deeds, records of Masonic Order, and miscellaneous.

Includes a complete set of the monthly periodical, The Medical World, for the year 1908.

Papers (1925-1978) consisting of a diary, copy of a manuscript, bulletins, newsletters, photographs, and miscellaneous material.