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Papers (1976-2011) of Secretary of the North Carolina Department of Environment and Natural Resources (DENR), Executive Director of the North Carolina Clean Water Management Trust Fund and lobbyist for Conservation Council of North Carolina and the Sierra Club, North Carolina Chapter, including correspondence, newsletters, pamphlets, handbooks, magazines, legislative summaries, memos, reports, newspaper clippings on microfilm and miscellaneous documents relating to environmental issues.

Collection (1733-1943) consisting primarily of Stallings family papers, deeds, land surveys, wills, a Bible record, newspapers, clippings and miscellaneous.

This collection contains the records of the former ECU News Bureau, including press releases, newspaper clippings, sound recordings of programming, and information about East Carolina gaining university status.

Issues of USS Princeton newsletters (1950-1951), including Morning Press News and Slipstream and U.S. Naval Training Canter, Sampson, N.Y. Publication Sampson News (1944).

Artwork and prints, primarily oversized, found in Country Doctor Museum items. Includes prints from "A History of Pharmacy in Pictures," "A History of Medicine in Pictures," "History of Anesthesia in Pictures," "Gay Philosopher" by Henry Major, "Pioneers of American Medicine" by Dean Cornwell, and other prints.

Collection (1902-2003) of genealogical and historical research files compiled by John Henry Oden III. Also includes the R. C. Chadwick Mercantile Records, Claude F. Pilley Papers, and the Windley Family Papers. Consists mostly of copies of wills, tax records, letters, deeds, newspapers, birth certificates, family trees, and photographs related to families in Beaufort, Washington, Hyde, and Halifax counties, N.C.

These papers (1918, 1935-2012) relate chiefly to renowned poet A. R. (Archie Randolph) Ammons and belonged to his sister Vida Ammons Cox. Included are correspondence, publications by or dedicated to A. R. Ammons, programs, posters, photographs, awards, broadsides, book reviews, audio recordings, watercolors painted by A. R. Ammons and newspaper clippings.

Records (1903-1954, undated) of the Leggett (NC) general store.

Includes a complete set of the monthly periodical, The Medical World, for the year 1908.

Records (1943–1946) of the escort ship USS Hopping (DE-155), attached to Escort Division 6 of the Atlantic Fleet during World War II and including war diaries, action reports, and miscellaneous material relating to U-Boat attacks, anti-submarine warfare, etc.

Papers (1762-1902, undated) documenting the life of the Noble family from the Chicod Township of Pitt County and the Creeping Swamp and Swift Creek areas of Craven County. The bulk of the collection includes material related to the activities of Celina Clark Noble (1829-) and her family and includes land records, land description and surveys, promissory notes, mortgages and other legal papers, bank notes, ballads, financial papers, receipts, etc. Also included is the Civil War correspondence (1864-1865) of Corporal E. E. (Evans Everette) Noble (1829-1895) of the 67th Regiment North Carolina Infantry to his wife Susan J. Noble (1837-1873) while serving throughout Eastern North Carolina.

The collection includes correspondence and some photographic material documenting the service of Richard Lewis Kinney (1927-2015) of Lexington, North Carolina in the United States Army in occupied Japan at the end of World War II. The collection provides a glimpse of an American soldier's point of view and experience serving overseas during the post-war occupation of Japan.

Collection contains a variety of items relating to Eastern North Carolina especially including a photograph of East Carolina Teacher's College scene (ca. 1940's); a theater Program (ca. 1933/34) for a play presented by The Episcopal Junior Guild, Austin Building, East Carolina Teacher's College; and a Measles in Quarantine Keep Your Babies Away From Measles Broadside (4/7/1934) posted on the home of Ella Viola McGowan when she had the measles. Also included are photographs (some unidentified) of World War II era of which several pertain to military bases such as the 657th Engineer Topographic Battalion (40th Infantry Division, U.S. Army), and one is of Cecil May in U.S. Marine corporal uniform; a photocopy of a letter (1913) containing reminiscences of Confederate veteran John W. Vernelson (of N.C. State Troops) war service and describing the Veterans Reunion at Gettysburg, PA; receipts (1909-1910) for sales by Crown Bottling Works in New Bern, NC; Pitt County, NC, land grants and deeds (1782-1837) related to the Boyd, Edwards, and Nobles families; Bible Records and birth and death records for the Eldridge, Wilder/Hatsell, Pittman, Moore, Sewell, and Davis families; and the book (2011) "One of the Lucky Ones," Edgar Cannon's Contributions in World War II. Other materials (1856-2001) consist of manuscripts, research clippings, notes, photocopies, photographic prints, programs, notebooks, and newspapers, relating to the history and genealogy of Eastern North Carolina, especially Robersonville and Williamston in Martin County, NC. Also included are a 1941 color silent 16mm film about Greenville and slides (ca. 1970) documenting tobacco and old houses in Pitt County, NC.

Various unrelated items (1862-1865) concerning the Civil War including two 1862 letters, an 1865 oath of allegiance, Harper's Weekly lithographs (1862), an Atlantic and North Carolina Railroad Company 1862 statement, an 1862 $1000 Civil War bond from North Carolina;, and photocopies of a memoir written about fifty years after the war and transcribed in 1978, an 1862 letter and an 1863 circular.

Papers (1865-1954, undated) consisting of correspondence, speeches, financial and legal records, a minute book, a guest register, photographs, newspapers, genealogical notes, deeds, etc., related to the career of Dr. Charles O'Hagan Laughinghouse (1871-1930) of Greenville, N.C., and to the Laughinghouse and related Stokes families. Besides having a successful practice in Greenville, Dr. Laughinghouse was a respected member of the North Carolina State Board of Health for several years beginning in 1911, served as president of the Medical Society of the State of North Carolina in 1916 and 1917, and served as State Health Officer from 1926 until his death in 1930.