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The Edward Baxter Billingsley Collection (1817-1819, 1938–1999, undated) consists of historical research materials, drafts, and a typescript copy (643 pages) of One Destroyer and World War II: A History of the U. S. S. Emmons (DD457-DM22), by Edward Baxter Billingsley, that he later published as The Emmons Saga: A History of the U. S. S. Emmons (DD457 – DM22). Also included are photographic prints, photocopied naval documents, and microfilm reels concerning his research, and correspondence (1817-1819) related to his dissertation on Chilean and Peruvian wars of Independence.

Papers, certificates, photos, and artifacts of Dr. Edwin Wall Monroe. This collection contains a great deal of information regarding the development of the East Carolina School of Medicine, including planning, politics, legislation, advertisement, construction, partnerships, details of the personnel involved, groundbreakings and other ceremonies, departments, additional buildings, and community services.

Papers (1866-1872) consisting correspondence to suitor, romantic and personal letters, receipt, bill of sale, difficulty of making train connection, dispute between older and younger, etc.

Papers (1777-2022) relating to John Baxton Flowers III academic career, family history and Scottish genealogy (Flowers, Kennedy, and Thompson families of Wayne County, NC), historic preservation, horticulture and garden history. Included are correspondence, financial and legal papers, academic records, newspaper clippings, photographs, typescripts, genealogical material, publications, certificates, house plans, watercolor drawings, and newsletters.

Papers (1788-1869, 1965) Hoyle J. Windley, of Bath, NC, a teacher, postmaster, and lieutenant in the NC militia, and his children, consisting of correspondence, store accounts, receipts, promissory notes, wills, summonses, bill of sale, special events-major fire, tournaments, coronation Ball, etc.

Contained in this collection are materials originally owned by Dr. William C. Groves including medical lecture tickets from Pennsylvania College and a patient's death certificate.

The collection has papers from the Massengill family, specifically John David, Samuel Evans, and Pauline (Massengill) DeFriece. Included are John's account books, booklets, DeFriece's correspondence with the Country Doctor Museum, photographs, and information about the S. E. Massengill Company.

Minutes (1859, 1880) including Blue Book containing Sons of Temperance rituals, note book containing minutes, list of members, notations, diagram, passwords, etc.

Letters written by Victor C. Faure to his parents dated from May 18, 1918 to 27 March, 1919. Describe movement from California to Fort Mills on Long Island, to France, and delays in returning home after the war.

U.S. Navy papers (1943-1945), primarily for the USS Chilton, USS Lyon, and USS Calvert, including training materials, rosters, communiques, debarkation instructions, morning orders, landing plans, plans of the day, and ship's newsletters.

Papers (1803-1957, undated) including correspondence, original poetry, essay, income from tobacco, Civil War causalities, pamphlets, ballot, deeds and indentures, genealogical records.

Papers (1876-1881) including correspondence, calling card, an invitation, letters.

Issues of USS Princeton newsletters (1950-1951), including Morning Press News and Slipstream and U.S. Naval Training Canter, Sampson, N.Y. Publication Sampson News (1944).