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Papers of Allen Tate (1927-1996, undated) documenting the life and literary career of the noted American poet, biographer, editor, essayist, novelist and educator, including manuscripts, proofs of published materials, printed materials & ephemera, loose manuscripts transferred from the Stuart Wright Book Collection, oversized materials, by or about Allen Tate, Ellen Glasgow, John Crowe Ransom, Peter Hillsman Taylor, Robert Penn Warren, Eudora Welty, and others; in English and Latin language.

Papers (1854 [1922]-1967) including correspondence, literary manuscripts, speeches, tape recordings, scrapbooks, photographs, newspaper clippings, pamphlets and miscellany.

Collection (1821-2000, undated [bulk: 1989-2000]) of correspondence, family histories, genealogical charts, copies of deeds, cemetery records, Bible records, miscellany and oversized materials relating to Christopher DeGraffenried, also known as Baron Christoph von Graffenried, who established a colony of Swiss and Palatine emigrants at New Bern, North Carolina, in 1710; and also relating to his ancestors and descendants and the DeGraffenried Association, of Gulfport, Mississippi and San Antonio, Texas, which was established to preserve the family history and to maintain contact between family members; in English, German, Italian, and French language.

This collection consists of original photographs, photographic prints (copies), negatives and proof sheets (ca. 1890-1900, 1950s -1970s) documenting history in and around the area of Murfreesboro, North Carolina. These consist primarily of images of businesses, buildings, boats and ferries, mills, cemeteries and gravestones, architectural features of interest, churches, schools, people and historical houses.

This collection contains about 363 cubic feet of material documenting the Congressional career of Lunsford Richardson Preyer. Mr. Preyer (January 11, 1919-April 3, 2001) of Greensboro, North Carolina, served in the U.S. House of Representatives for twelve years (January 1969-January 1981).

Records (1919-2016) of the Rotary Club of Greenville, North Carolina, including correspondence, minutes, financial papers, deeds, membership lists, publications, scrapbook, clippings, motion picture film, audio tapes, photographs and memorabilia.

Private journals/ships' logs (October 1860 - July 1878) of Benjamin Thompson, master of the brigs Progressive Age and T. A. Darrell, and the ships Sportsman, and Harrisburg (v. 1, 1860-1865), commander of the ship Columbia (v. 2, 1865-1870), master of the ship Peruvian (v. 3, 1870-1872), and captain of the clipper ship Great Admiral (v. 4, 1874-1878), illustrating his career aboard sailing ships trading between England, the east and west coasts of America, Southeast Asia (Singapore, Manila, and Hong Kong), and Tokyo, Japan, including highly detailed and dramatic accounts of shipboard life and commercial operations.

Papers of Andrew Nelson Lytle (1934–1992, undated) documenting the life and literary career of the noted Murfreesboro, Tennessee-born, American biographer, novelist, dramatist, literary critic, educator, and editor, who became a leader and spokesman for the Southern Agrarian literary movement, including correspondence, manuscript materials, typescripts and holographs, printed materials, and loose manuscript items transferred from the Stuart Wright Book Collection.

Papers (1873, 1892-2009, undated) concerning Littleton Female College (later called Littleton College) in Warren County, North Carolina, and its alumnae include correspondence, programs, college history, alumnae lists, clippings, pamphlets and speeches, etc. The college opened in 1882 and closed after a disastrous fire in 1919. The Littleton College Memorial Association was founded in 1926.

Journal of a Cruize in the USS Independence, Commodore William Bainbridge's Flag Ship, Capt. William M. Crane, Commander, from Boston, July 2nd, 1815 (3 July–15 November 1815), compiled by an anonymous crew member, which describes the first overseas mission of the first ship of the line commissioned by the United States Navy, to deal with the piratical acts of the Barbary Powers against American merchant commerce in the Mediterranean Sea, bound in original calf leather over marbled boards, entries clean and legible; also a letter from William M. Crane, Commanding Officer, USS Delaware, Port Mahon (20 September 1829) to Lt. William N, McKean, U.S. sloop Warren, ordering him to report to Lt. Thomas M. Newell, commander of the U.S. schooner Porpoise.

William "Bill" Cain papers contain materials from his career at ECU and personal items.

Papers (1764-1910) including correspondence, land records, account sales, a photograph, agricultural reports, receipts and miscellaneous.

Papers (1940–1945) of a U.S. Naval Reserve medical officer, including scrapbook of clippings, photographs, correspondence, photographs, original art, and memorabilia compiled while serving in the U.S. Naval Reserve at the Toledo, Ohio naval recruiting station, 1942–1943; And letters sent to his parents Dr. and Mrs. Carroll C. English, in Louisville, Kentucky, while serving aboard USS Trathen (DD-530), 4 April 1943–5 December 1944

Papers (1865-1954, undated) consisting of correspondence, speeches, financial and legal records, a minute book, a guest register, photographs, newspapers, genealogical notes, deeds, etc., related to the career of Dr. Charles O'Hagan Laughinghouse (1871-1930) of Greenville, N.C., and to the Laughinghouse and related Stokes families. Besides having a successful practice in Greenville, Dr. Laughinghouse was a respected member of the North Carolina State Board of Health for several years beginning in 1911, served as president of the Medical Society of the State of North Carolina in 1916 and 1917, and served as State Health Officer from 1926 until his death in 1930.