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This collection contains materials that date from Dowell's time as a student at East Carolina Teachers Training school and her subsequent teaching career. It contains awards received from both civic and professional organizations, clippings, personal artifacts, and scholarly works including her Masters Thesis.

Papers (1943–1945) including copies of correspondence, personal notations, orders, addresses, photographs, reminiscences, equipment lists, and reports pertaining to his World War II service with the 14th Malaria Control Unit of the U.S. Army Air Corps in New Guinea and the Philippines, 1943–1945, including references to malaria control, military issues, and incidents involving Japanese, American and Filipino forces.

Personal papers of Lieutenant Colonel Luther G. Williams, Jr. (1943-) of Greenville, North Carolina, documenting his childhood, family, education, military service, and Civil War research.

This collection contains materials from professor emeritus Julie Fay's time at East Carolina University including materials about the Readers Writing Series, which she organized, the English Department, and materials regarding projects documenting the aftermath of Hurricane Floyd in Eastern North Carolina. It also contains materials related to her poetry and publications, as well as personal items and ephemera.

Papers (1865-2013, bulk 1919-1982) relating to Georgia Pearsall Hearne, an artist, musician, and teacher, whose portraits of prominent North Carolinians earned her state-wide recognition, including consisting of correspondence, daybooks, photographs, original artwork, reproductions of art work, newspaper clippings, printed forms, printed materials, genealogical materials, and miscellany.

Collection (1763-2013) including correspondence, financial records, legal records, clippings, land records, photographs, clippings, poetry, genealogy and miscellaneous files compiled by William L. Murphy related to genealogy research in Eastern North Carolina.

Papers (1804-1968) consisting of correspondence, financial records, deeds, records of payments, weighting receipts, taxes, tax lists.

Records (1987-2004) of the North Carolina Chapter of the Sierra Club pertaining to conservation issues in North Carolina, including correspondence, reports, directories, newsletters, financial records, membership and staff records, meeting agendas and minutes, printed materials, etc.

Documents pertaining to World War II activities of a squadron designated at various times as Bombing Squadron 106 (1943-1944), Patrol Bombing Squadron 106 (1944-1945), and Patrol Squadron 106 (1945-1946), including historical summaries, action reports, war diaries, interviews operational orders, articles, rosters, etc.

Collection (1841-1959, undated) of manuscripts, genealogical materials, photographic prints and printed materials related to the James N. Dickey family of New York and Michigan and William Symington Brown, M. D., who served as a surgeon in the 33rd and 55th Massachusetts Infantry Regiment, 1863, during the Civil War. Unrelated is a photograph of U.S. Vice President Barkley attending a Roosevelt Dinner held at East Carolina Teachers College (now ECU) in 1950.

This collection (1942-1999) contains papers related to the World War II service of Lt. Commander Godfrey Cheshire, Jr., in the Pacific Theatre aboard the USS Harold C. Thomas (DE-21) for which he was the commander for a year. Included are photocopies of the ship's logs for the USS Harold C. Thomas, correspondence (1990-1992) with the Destroyer Escort Commanding Officers Association about reunions, Cheshire's military records (1942-1945, 1947), photocopies of clippings and articles about the Thomas and other DEs, photocopies of certificates, photographs, and DVDs containing oral history interviews of Cheshire by family members.

Papers (1942-1946, 1951, 1991), of U.S. Naval photo interpreter and intelligence officer, including memos, photographs, pamphlets, operations manuals, worksheets, maps, reports, and ephemera reflecting operations at Normandy, Cherbourg, Sicily, and Guam during World War II.

Papers of Eve Shelnutt (1984) documenting the life and literary career of the Spartanburg, South Carolina-born American poet, short story writer who taught creative writing at various universities, including the College of the Holy Cross; consisting of unbound carbon typescripts of her volume of poetry Air and Salt (1984) and of her short story Undersong (1984).

Papers of Walker Percy (1954-1997 [1975-1987]) documenting the life and literary career of the noted Birmingham, Alabama-born American novelist of the New South, consisting of three copies of a proof entitled Walker Percy: A Bibliography: 1930-1984, compiled by Stuart Wright (1985); also loose manuscript items transferred from works by Walker Percy in the Stuart Wright Book Collection, including from: Lancelot: A Novel (1977-1982), Lost in the Cosmos (1978-1997), The Message in the Bottle (1975-1983), The Movie-Goer: A Novel (1961, 1982), The Thanatos Syndrome (1987-1997), The Correspondence of Shelby Foote Walker Percy (1979-1987), The Message of Auschwitz (1987), and Walker Percy: A Bibliography, by Stuart Wright (1986) ; also including a pamphlet by Walker Percy, entitled Symbol and Need (1954).