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Papers (1777-2022) relating to John Baxton Flowers III academic career, family history and Scottish genealogy (Flowers, Kennedy, and Thompson families of Wayne County, NC), historic preservation, horticulture and garden history. Included are correspondence, financial and legal papers, academic records, newspaper clippings, photographs, typescripts, genealogical material, publications, certificates, house plans, watercolor drawings, and newsletters.

Papers (1923-1986) including correspondence, orders, reports, newsletters, photographs, news clippings, scrapbooks, programs and miscellany.

Collection (1760-1940) including land grants, deeds, bill of sale of enslaved persons, correspondence, Civil War documents, and an account book, pertaining to the land holdings and genealogy of the McIver, McLeod, Lane, Crawford, Mumford, and Faison families of Moore, Chatham and Columbus counties, North Carolina.

Articles, papers, and slides belonging to dentist and periodontist, Paul M. Cummings Jr.

Personal files created by Pitt County, North Carolina, native Mary Perkins-Williams relate to the Pitt County Black Assembly (1979, 1983), NAACP Legal Defense (1980), regional development (1977-1979), minority issues, and fair housing. Audio-Visual Materials include photographs of scrapbook images (ca. 1950s) documenting both abandoned and active Pitt County, North Carolina, African American public schools. Also included are seven videocassettes documenting a grant-funded oral history project completed in 1994 entitled Growing up African-American in Pitt County.

Collection (ca. 1930–1954) manuscript and printed materials relating to the early history of Pitt County, North Carolina, and the Greenville High School Class of 1946, including revised manuscript drafts of a history of Pitt County, including correspondence, clippings, brochures, pamphlets, maps and rationing labels.

The Rich Elkins Papers (1994-2002) is a collection of publications and clippings on the Lesbian, Gay, Bisexual, and Transgender communities in North Carolina, South Carolina, and New York with some of the materials from the LGBT community in Greenville, N.C. located in Eastern North Carolina. Richard "Rich" Elkins has been active in the Eastern N.C. LGBT community for many years and these materials reflect his involvement.

Collection includes papers related to the personal life and non-university activities of East Carolina University History Professor Lawrence Fay Brewster (ECU professor from 1945 to 1969) for whom the Lawrence F. Brewster Classroom Building on campus was named in 1974. Included are materials (1857-1945) related to his parents and ancestors, Brewster's early life and education through earning his Ph.D., his teaching job at Cranleigh School for Boys in St. Petersburg, Florida, and his work with the Works Progress Administration as Research Editor for the Historical Records Survey of North Carolina. The vast majority (1960-1991) of the collection concerns his work as historiographer for the Episcopal Diocese of East Carolina and writing his "History of the Protestant Episcopal, The Diocese of East Carolina."

This collection contains issues of the Treasure Chest Newsletter issued by Academic Library Services' Teaching Resources Center.

The Henry Ferrell Papers include professional and personal correspondence, committee and departmental reports, materials related to his scholarly works and research, including the book "No Time for Ivy," and materials related to his participation in professional and civic organizations.

This collection contains materials related to an assignment, "Draw History and Draw the Course", that Dr. Kenneth Wilburn used in many of his courses from 1984 to 2014.

Papers (1760 [1880] - 1935) including correspondence, financial papers, account books, daybooks, essays, speeches, legal records, land records, notebooks, etc. of Eastern North Carolina farmer, leader of the NC Tobacco Growers Association, and NC Secretary of State (1901-1923), etc.

Account books, handwritten notebook, and miscellaneous papers from Dr. H.H. Whitaker. The handwritten notebook includes symptoms, treatments, prognosis, and other valuable information about a wide range of illnesses. Miscellaneous papers include draft copies of deed contracts, correspondence, and receipts.

Collection (1794-1951, 1971, undated) including correspondence, deeds, statements, promissory notes, will, inventories, legal papers; poems, clippings, photographs, etc. relating to the Banks and Stacey families.

Papers (1870-1981) including correspondence, legal documents, ledgers, literary manuscripts, stock certificates, deeds, charters, minutes, photographs, clippings, financial records, orders and publications.