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The papers track the history and development of Pitt County Memorial Hospital(previously Vidant, now ECU Health) and Brody School of Medicine, including scrapbooks, photographs, publications, and videos.

Papers of John Crowe Ransom (1904-2000, undated) documenting the life and literary career of the noted Pulaski, Tennessee-born American editor, poet, literary critic, and educator, including correspondence, manuscripts, photographic prints, proofs of published materials, printed material, audio recordings, loose manuscript items transferred from the Stuart Wright Book Collection and oversized materials, by or about W. H. Auden, Christopher Isherwood, T. S. Eliot, Robert Penn Warren, Richard Ghormley Eberhart, Randall Jarrell, Katherine Anne Porter, William Styron, Allen Tate, Peter Hillsman Taylor, and others, in English and French language.

Papers of William Goyen (1935-1999, undated) documenting the life and literary career of the noted Trinity, Texas-born, American novelist, short story writer, poet, playwright, editor and educator at several schools, including Brown University; consisting of loose manuscript items transferred from the Stuart Wright Book Collection, including manuscripts, notes and clippings by or about William Goyen, D. H. Lawrence, Merriam Golden, Stephen Spender, and others; also including printed materials.

Records (1888-1968) including correspondence, legal records, reports, photographs.

Seven engravings of University of Pennsylvania medical school faculty.

Papers (1911-1968, undated) include correspondence, writings, legal and financial papers, news clippings, a photograph and miscellaneous documents related to the career of Harry V. Bernard, Sr., who was an American businessman in China beginning in 1911. The documents also reflect his work with flood relief in the Shanghai District of China in the 1930s and his internment by the Japanese in a prison camp near Shanghai during World War II.

Papers (1907-1968) documenting the U.S. Naval career (1910-1946) of Admiral Jules James consisting of correspondence of Naval travels, logbook, diaries, newspapers clippings, radio press news.

Papers (1887-1933) including diaries, medical school notes, school register, ledger, daybooks, memo books, clippings, physician's birth record stub book, a funeral memorial record, a photograph and miscellany.

Papers (1905-1999, undated) consisting of correspondence, minutes, reports, rosters, speeches, pamphlets, publications, yearbook, programs, clippings, photographs, farm ledgers, notebooks, bulletins, brochures, date book, deposition, will, contracts, inventory and poetry related to teacher Blanche Hardee Rives (1887-1973)and her family in Enfield, Halifax County, North Carolina. Also documented are her involvement in the Methodist Protestant (United Methodist Church after 1939),the Hardrawee Home Demonstration Club, the Halifax Co. Home Demonstration Club, Order of the Eastern Star, Halifax County Historical Association, Northeastern North Carolina Branch of the English-Speaking Union, Frank M. Parker Chapter of the United Daughters of the Confederacy, and Littleton College Memorial Association.

Papers (1945, 1993) including correspondence, typescript article, letters, "The WAUKESHA, Hiroshima, Nagasaki and the Atomic Bomb,: and a resume.

Papers (1775 [1932-1966] - 1980, undated) consisting of correspondence, speeches, a diary, essay, reports, photographs, an autobiography, scrapbooks, newspaper clippings, maps, pamphlets, financial records and miscellany.

Contains photographs by Jan Sellers Cowards of Eastern North Carolina.

Papers of Robert Penn Warren (1885-2008 [Bulk: 1940-1989], undated) documenting the life and literary career of the noted Guthrie, Kentucky-born American poet, novelist, playwright, biographer, and educator, who played a major role in the rise of the Fugitive and Agrarian literary movements and in the spread of the New Criticism during the mid-20th century, and who became the first poet laureate of the United States, including correspondence; manuscripts, photographic prints, proofs of published materials, printed material, loose manuscript items from the Stuart Wright Book Collection, audio recordings and oversized materials, by or about Robert Penn Warren, Cleanth Brooks, John Ciardi, Annie Dillard, Fred Chappell, Richard Ghormley Eberhart, Robert Frost, George Garrett, Randall Jarrell, Robert Lowell, Bernard Malamud, Albert J. Montesi, John Crowe Ransom, Theodore Roethke, William Carlos Williams, and others; in English, Dutch, and Latin language.

Frank H. Price, Jr., a graduate in the USNA Class of 1941, had a naval career including service in World War II through postwar work with developing conventional warheads for Navy guided missiles and commanding several ships and a Destroyer Division, culminating in promotion to vice admiral in 1972 and retirement in 1975. His papers cover his entire naval career and include correspondence, orders, a memoir, clippings, photographs, programs, publications and a photograph album.

Lemuel Showell Blades, III, (1933-2011) began his career as a lawyer and then went on to become the president of the Norfolk Telephone Company while serving on a number of committees in Elizabeth City, and New Bern, North Carolina. This collection spans from 1711-2011 and includes newspaper clippings, photographs, genealogical charts, letters, oral histories, books, videos, and career files. The strength of this collection is the genealogical overview of the several generations linking to the Blades family.