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Papers of Merrill Moore (1929–1987, undated) documenting the life and literary career of the noted Columbia, Tennessee-born American poet, physician and psychiatrist, who became a leader and spokesman for the Fugitive Group of Southern poets that included Robert Penn Warren and Allen Tate, among others; including correspondence, manuscript materials, printed materials and loose manuscript materials from the Stuart Wright Book Collection.

Included is genealogy correspondence written to and from Al Jones accompanied by pedigrees, family group sheets, and family histories (most written by Al Jones). Material is filed alphabetically by correspondents' last names. The main focus is the Jones family of Blount's Creek, Beaufort County, North Carolina, and related family lines including, among others, Tuten, Cratch, Stilley, Roe/Row, Orrell, Galloway, Searles, Harding, and Purefoy, and Pridgen.

Correspondence, photographs, postcards and printed material documenting North Carolina history. Locations include Fayetteville, Elizabeth City, High Point, Wilmington, Atlantic Beach, Morehead City, Belhaven, Edenton, Pitt County, Camp Lejeune, Reidsville, Rocky Mount, St. Pauls Washington and New Bern. Subjects include the Askew Family of Hertford County, Greensboro College, Fayetteville flood of 1908, the Confederate Ram Albemarle and the tobacco industry.

The John W. Warner Papers (1947-1986) document the career of filmmaker and entrepreneur John W. Warner, with a primary focus on the creation, financing, distribution, and later rediscovery of the independent film Pitch A Boogie Woogie. Dating chiefly from 1946 to 1958, with additional materials from 1986, the collection includes correspondence, legal and financial records, promotional materials, memorabilia, scripts, photographs, and audiovisual media that illuminate the business and creative challenges of independent filmmaking in the mid twentieth century. Supplementary materials reflect Warner's broader professional activities in North Carolina, including television production and local theater operations. Together, the papers provide insight into regional film production, film exhibition and promotion, and the processes through which a largely forgotten work was reclaimed and recontextualized by scholars and the public decades later.

Collection of eastern North Carolina folklore student research projects based upon interviews with family, friends, and acquaintances completed for folklore classes at East Carolina University, Greenville, N.C.

Collection contains a scrapbook (1943-1945) related to Betty Bonner Higgins' World War II service in W.A.V.E.S (Women Accepted for Volunteer Emergency Service). Included is an assortment of photographs of her family, of herself and her fellow W.A.V.E.S. during training at Indiana University, and of her boyfriend aboard the USS Admiralty Islands and soldiers in the Pacific Theater. Assorted military notices, newspaper clippings, ephemera, personal correspondence, and two pamphlets describing service in the W.A.V.E.S. are also in the scrapbook.

Collection consists of copies of the Mellette Family History, and a History of Pleasant Hill Masonic Lodge, No. 304.

In this oral history interview, Joseph Crutchfield, Jr. speaks about his childhood, his experiences as a student at East Carolina University, his career as a teacher, and his involvement in indigenous organizations.

Papers (1776-1860) including deeds, and a promissory note concerning Halifax County (N.C.) property.

Papers of Flannery O'Connor (1962-1984, undated) documenting the life and literary career of the noted Savannah, Georgia-born American short story writer & novelist in the Southern Gothic style, consisting of a broadside entitled Higher Education [Poem] by Mary Flannery O'Connor. Palaemon Broadside No. 16 (Palaemon Press, Ltd., undated); also mimeographed, photocopied typescripts, clippings, letters, and an audio recording of Some Aspects of the Grotesque in Southern Fiction, a speech given by Flannery O'Connor in 1960.

The Neyuherú·kęʼ Wampum Belt tells a story of the Tuscarora Nation's experience in North Carolina and New York. It is sacred to the Tuscarora people. The Neyuherú·kęʼ Wampum Belt was presented to the "people of North Carolina" and accepted by then Provost Marilyn Sheerer and ECU on behalf of North Carolina in 2013 to commemorate the 300th anniversary of the Neyuherú·kęʼ Battle. Alternate spellings are Noherooka and Neoheroka.

The Goldsboro Messenger Map of North Carolina, 1879, with Beaufort Harbor Inset Map, (New York, NY: G. W. C. B. Colton Co.) was a foldout map contained in a handbook given as a premium to subscribers of the Goldsboro Messenger. The handbook contains useful information about North Carolina.

Books, pamphlets, and a notebook belonging to Dr. Charles Barker.

Lemuel Showell Blades, III, (1933-2011) began his career as a lawyer and then went on to become the president of the Norfolk Telephone Company while serving on a number of committees in Elizabeth City, and New Bern, North Carolina. This collection spans from 1711-2011 and includes newspaper clippings, photographs, genealogical charts, letters, oral histories, books, videos, and career files. The strength of this collection is the genealogical overview of the several generations linking to the Blades family.

This collection contains student handbooks that include university hours, campus calendars, and social regulations.