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The papers track the history and development of Pitt County Memorial Hospital(previously Vidant, now ECU Health) and Brody School of Medicine, including scrapbooks, photographs, publications, and videos.

Papers (1870-1950, undated) of clerk of Pitt County Superior Court and his sons, consisting of correspondence, land records, legal records, pamphlets, reports, essay, poems, receipts, speeches, ledger books, and miscellaneous.

Papers of William Goyen (1935-1999, undated) documenting the life and literary career of the noted Trinity, Texas-born, American novelist, short story writer, poet, playwright, editor and educator at several schools, including Brown University; consisting of loose manuscript items transferred from the Stuart Wright Book Collection, including manuscripts, notes and clippings by or about William Goyen, D. H. Lawrence, Merriam Golden, Stephen Spender, and others; also including printed materials.

March 9, 1861, issue of the Weekly National Intelligencer, a Washington, D.C., newspaper.

Papers (1772, 1816-1927) including correspondence, legal papers, deeds and estate papers, financial papers, speeches, stories and poems, clippings, photographs, ledgers, medical bills, services rendered, charges and payments, etc.

Papers (1791, 1846-1941) including correspondence, diaries, visitation books, account books, memoranda books, financial papers, minute books, photographs, land records and miscellaneous.

Seven engravings of University of Pennsylvania medical school faculty.

Papers (1911-1968, undated) include correspondence, writings, legal and financial papers, news clippings, a photograph and miscellaneous documents related to the career of Harry V. Bernard, Sr., who was an American businessman in China beginning in 1911. The documents also reflect his work with flood relief in the Shanghai District of China in the 1930s and his internment by the Japanese in a prison camp near Shanghai during World War II.

Papers (1907-1968) documenting the U.S. Naval career (1910-1946) of Admiral Jules James consisting of correspondence of Naval travels, logbook, diaries, newspapers clippings, radio press news.

Papers (1775 [1932-1966] - 1980, undated) consisting of correspondence, speeches, a diary, essay, reports, photographs, an autobiography, scrapbooks, newspaper clippings, maps, pamphlets, financial records and miscellany.

Papers (1887-1933) including diaries, medical school notes, school register, ledger, daybooks, memo books, clippings, physician's birth record stub book, a funeral memorial record, a photograph and miscellany.

Papers (1831-1946) including correspondence, legal and financial papers, newspapers, articles on local business, hotels, banks, and miscellaneous.

Papers (1945, 1993) including correspondence, typescript article, letters, "The WAUKESHA, Hiroshima, Nagasaki and the Atomic Bomb,: and a resume.

Papers (1830-1919) of a prominent New Bern, NC attorney, state representative, 1876-1880, and state senator, 1881-1883, consisting of correspondence, legal briefs, financial papers, accounts, estate papers, land book and miscellaneous.

Contains photographs by Jan Sellers Cowards of Eastern North Carolina.