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The papers track the history and development of Pitt County Memorial Hospital(previously Vidant, now ECU Health) and Brody School of Medicine, including scrapbooks, photographs, publications, and videos.

Papers, 1861-2011 (bulk 1940-1992), undated, of Senator Robert Burren Morgan, an ECU alumnus and lawyer, who served the state of North Carolina in a variety of elected and appointed positions. His first elected position was clerk of court in Harnett County. He was elected to the State Senate, served as president pro tempore of the Senate, and was twice elected Attorney General of North Carolina. He served in this position until 1974, when he won the United States Senate seat vacated by Senator Samuel James "Sam" Ervin, Jr. Morgan served as United States Senator from 1975 to 1981. He returned to his law practice following an unsuccessful reelection campaign and later served as Director of the State Bureau of Investigation from 1985 until 1992. Morgan served as a member of the ECU Board of Trustees for fifteen years, including nine terms as chair in the 1960s. He helped the institution achieve university status and was instrumental in establishing the ECU School of Medicine. The collection includes series relating to Morgan's family and personal matters, North Carolina Senate Files, Attorney General Files, United States Senate Files, North Carolina State Bureau of Investigation Files, and Oversized Materials Files. It includes manuscripts, photographs, audio and video materials, electronic records, printed materials, and ephemera.

Memoir of a white supremacist group, the Ku Klux Klan, activities in North Carolina and South Carolina during the Reconstruction Era. (undated)

This collection contains records of awards won by Creative Services as well as samples of print designs created by the department.

This collection (1791-1960) documents the horse and mule business, farm operations, land transactions, saw mill operation, and other business enterprises of Edward Cyrus Winslow (b. 1886) of Tarboro, Edgecombe County, N.C. Included in the collection are correspondence, financial and legal records such as account books, ledgers, bills and receipts, contracts with other mule dealers, promissory notes, agricultural liens and chattel mortgages, deeds, and lease and rental agreements. Also included are superior court records, blueprints of farm tracts and dairy equipment, printed material, business and family photographs, and a small quantity of family correspondence.

This collection contains digital materials from the Center for Survey Research, specifically survey reports.

Records Palaemon Press, Limited (1943-1992, [Bulk: 1977-1987], undated) documenting the history and publications of the small, Winston-Salem, North Carolina literary press, that produced small, beautiful, numbered editions of brochures, broadsides, chapbooks, & pamphlets, mainly by southern authors, owned and operated by Stuart T. Wright; consisting of correspondence with authors, printers, reviewers, and publishers; manuscript materials, loose manuscript items transferred from the Stuart Wright Book Collection, printed materials, proofs, and oversized materials.

Collection (1901-1926) of correspondence received by Maud Smith (née Tyson) and her husband Walter Edward "Edd" Smith, from family and friends. Collection includes letters to Maud Tyson, while she attended Littleton Female College, letters from Carl Tyson, during World War I, from the Headquarters of the 81st Division, at Camp Jackson, South Carolina, between May and November, 1918, and several other letters, as well as a list of transcripts and typed transcripts of all letters in the collection.

"The Abbott Alkaloidal Laboratory Products Trade Price List" pamphlet.

Papers (1811-1958) of A. D. Peace and Samuel Peace, and Matt Hankins, relating to Trinity College, North Carolina, Civil War battles at Washington, NC, Rappahannock Bridge, and Kelly's Ford, VA, including of copies, a memoir, clippings, genealogical notes, financial account, Bible records, amateur verse, contract, account of medical services.

Photocopies of a diary (May 30-Aug. 7, 1862) kept by Alfred F. Williams of the 1st North Carolina Cavalry during the Civil War covering troop movements, his capture, and his exchange. Also includes a general store account record (1865-1867).

This collection consists of 48 deeds (1801-1907), legal documents and notes related to land ownership in Pitt County, North Carolina, in the area that became Ayden. The documents pertain mainly to the Harris, McGlohon/McLawhorn, and Cannon families, especially William Henry Harris, the founder of Ayden. Also included are a blueprint plat of Ayden (June 21, 1890) and copies of 2 clippings (1991-1992) about the founding of Ayden. Additional items which have been placed in the East Carolina University Archives are a 1915 yearbook for East Carolina Teachers Training School (now ECU), a 1915 folded card for the Junior-Senior Reception at ECTTS, and a calling card all belonging to ECTTS student Katherine (Kate or Katie) Eugenia Sawyer. This collection is donated by the family of John William Sawyer.

Papers (1736–2018) including correspondence, financial documents, legal documents, personal and family materials, printed materials, and photographic materials collected by E. Frank Stephenson Jr. relating to the Benjamin B. Winborne Family, the R. J. Gatling Family, E. Frank Stephenson Jr., and other people in North Carolina and Virginia, especially the Murfreesboro, North Carolina, area. The documents were collected by E. Frank Stephenson Jr. for research use while writing numerous historical publications and to make the items available for other researchers to utilize. Many of Mr. Stephenson's publications are also included in the collection.

This collection contains copies of ECU Magazine, which features information on East Carolina alumni and their accomplishments.

Papers (1939-1952) consisting of correspondence, orders, reports, memos, newsletters, clippings, post cards, financial records, and miscellaneous.