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The U.S. Navy Memorial Foundation Collection: Thomas Onachila Jr. Papers consists of two photographs documenting the USS Leyte (CV-32), an Essex-class aircraft carrier active during the early Cold War and Korean War period. The images, dating circa 1950–1952, include a view of the vessel and a group portrait of its crew.

Eliza Arnold Hopkins Poe was born in 1787 in London. She was an actor and mother of American Poet Edgar Allan Poe. The collection is a photographic print of a miniature portrait of Elizabeth Arnold Hopkins Poe dated circa 1811. It was donated to the East Carolina Teachers Training School's Edgar Allan Poe Literary Society in 1914.

Ledgers (1799-1861, 1911-1917) of Samuel R. Fowle Company of Washington, N.C.

This collection contains correspondence, publications, press releases, and administrative records related to the administration and competition of intramural and collegiate sports teams at East Carolina.

Diaries, journals and letters (1897-1906, 1986-1988) of Mormon missionaries in Eastern North Carolina (1897-1906), including William A. Adams, 1900-1902, James Godfrey, 1899-1901, William M. Hansen, 1897-1898, William R. Hobbs, 1901-1903, Lewis Johnson, 1903-1905, William A. Petty, 1905-1906, and James Taylor, 1900-1902, along with Memoirs, Notes, clippings, anecdotes and other materials compiled by Joel Grant Handcock, for use in the book Strengthened by the Storm.

Advertisements for medicine, likely from between 1870 and 1910. The advertisements include patent medicine trade cards, blotter paper advertisements, broadside advertising sheets, booklets, and calendars. "Patent medicines" were often promoted as "cure-alls" for many parts of the body and their ingredient list (if any) was often inaccurate.

Ledgers, day books and other records (1920-1980), of Falkland, NC Mercantile business and its antecedent firms.

Papers (1933-1988, undated) documenting the life and literary career of Katherine Anne Porter (1890-1980), the noted Indian Creek, Texas-born American short story writer and novelist, including correspondence; also original art, photographic prints, printed material and loose manuscripts transferred from the Stuart Wright Book Collection pertaining to Robert Penn Warren, Robert Lowell, Richard Ghormley Eberhart, William H. Littlefield, and others.

Papers (1863-1864) consisting of diaries with activities of battle.

This collection contains the congressional files for U.S. House of Representatives member Walter B. Jones, Jr., who represented the 3rd Congressional District of North Carolina from 1995 until his death in 2019. Included are files, scrapbooks, media, and electronic files. The electronic files were created by his staff and included speeches, correspondence, articles, promotional material, notes and videos for the years 2005-2018.

Collection (1803-1996) pertaining to Martin County, NC, farmer John Conrad Getsinger, Sr., (Nov. 4, 1812-Jan. 16, 1891), a native of Wurttemburg, Germany, and several of his descendants consisting of correspondence, memoranda books, a sketchbook created by Mr. Getsinger while he was a soldier (1847-1848) fighting in the Mexican War, financial records, Civil War records pertaining to Mr. Getsinger and his son John C. Getsinger, Jr., religious publications, Primitive Baptist Church records (especially for Smithwick's Creek Primitive Baptist Church), pamphlets, broadsides, photographs, legal papers, newspaper clippings, and miscellany.

Records Palaemon Press, Limited (1943-1992, [Bulk: 1977-1987], undated) documenting the history and publications of the small, Winston-Salem, North Carolina literary press, that produced small, beautiful, numbered editions of brochures, broadsides, chapbooks, & pamphlets, mainly by southern authors, owned and operated by Stuart T. Wright; consisting of correspondence with authors, printers, reviewers, and publishers; manuscript materials, loose manuscript items transferred from the Stuart Wright Book Collection, printed materials, proofs, and oversized materials.

Papers (1884-1912) consisting of correspondence and pamphlet

This collection contains a single Civil War Diary (October 1, 1862 - March 24, 1863) kept by William H. H. Leach.

This collection contains letters (1964-1967) written by brothers Terrence and Dennis Miller of St. Louis, Missouri, who joined the U.S. Army during the Vietnam War. Letters written by Dennis Miller during 1967 document his time serving in Vietnam as part of 3rd BN, 60th Ord Co. Also included are letters written by fellow soldiers and friends (through 1971), service records, negatives, military payment certificates, and Vietnamese money.