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Papers (1800-1961) of Hertford County, NC, family, consisting of correspondence, legal documents, financial papers, estate papers, account books, ledgers and time books, and miscellany, including records of Petty Shore Fishery and the family cotton business.

Papers (1937–1950) of U.S. Navy officer, U.S. Naval Academy class of 1941, including correspondence and grade reports of USNA; rosters, photographs, and bulletins from the USS New Mexico (BB-35); newsletters, photographs, and clippings from the USS Quincy (CA-71); Carrier Division 5 (CTF-77) and miscellany.

The papers track the history and development of Pitt County Memorial Hospital(previously Vidant, now ECU Health) and Brody School of Medicine, including scrapbooks, photographs, publications, and videos.

Reminiscences (1999) of Capt. Walter P. Murphy, Jr. (US Navy ret.) a member of the U.S. Naval Academy Class of 1941, of his service (1941-1944) as a junior naval officer during World War II, including among other topics the incident of the submarine USS Sailfish sinking the Japanese carrier Chuyo.

This collection contains over 100 letters (1885, 1892-1897) written to Sallie Dromgoole Cotten (1876-1972), daughter of Sallie Swepson Southall Cotten and Robert Randolph Cotten, either while she was at home at Cottendale in Falkland, Pitt County, North Carolina, or at Notre Dame of Maryland Preparatory School and Collegiate Institute in Baltimore. The letters are written mainly by Sallie's female friends, but also some male friends in the 1890s (1892-1897) The correspondents are family, associates, and friends, especially schoolmates. Topics are mainly related to interests of college women and men. Also included are ephemera such as dance cards and dance invitations especially to "German" dances which were large popular events among wealthy white families in Eastern North Carolina tobacco towns in the 1890s.

Records (1797-1956) including correspondence, ledgers, financial records, legal records, clippings, photographs, publications.

Collection (1802-1863) of a New York family including correspondence from England,

Included are a copy of the Daniels-Murphrey Family History compiled and edited by Eleanor Daniels Casey in 1993, a photograph of the USS Nebraska that Benjamin Daniels of Wayne County, North Carolina, sailed to Europe on in WWI, and three photographs of Benjamin Daniels in his WWI US Navy uniform.

Papers (1943) including correspondence, and an abstracted account of this correspondence entitled "Loneliness and Humor, Frustration and Pride."

This collection consists of photographs, slides, and negatives of images used in Greenville—Pitt County Chamber of Commerce, Inc. (North Carolina) publications in the 1970s through 1990s. Also included are some audiotapes.

This collection contains twenty-four pages of genealogical notes related to Beaufort County, N.C., families including Bonner, Snoad, Smallwood, and Latham written by Lucretia Hughes of Washington, N.C.; and a scrapbook of "About Town" columns (1946-1947) written by Penelope Bogart (Rodman) as a teenager for the Washington Daily News published in Washington, N.C. Also included are two typescripts of interviews done in 1938 with a mill worker at Glen Raven Cotton Mill in Burlington, N.C., and with a woman who ran a lodging house in Raleigh, N.C.; and an undated typescript titled "Description of Mill Village" about life on Factory Hill where many of the Asheville Cotton Mill workers lived. The interview with the woman in Raleigh also includes her experiences during the Civil War in Wake County, N.C. In addition, there is an errata of corrections to Van Camp's Images of America: Washington, North Carolina and a Bible containing family history information.

Collection (1899-2004) of printed materials compiled for the centennial of the Orville & Wilbur Wright's first flight at Kitty Hawk, North Carolina; including an article written by the Wright brothers on their flight experiments with various airplanes coupled with printed copies of photographs and a printed reproduction of the article; also copies of Monthly Weather Review magazines from August-September 1899; and a copy of the North Carolina Literary Review dedicated to commemorating the centennial of the first flight complete with poetry and interviews; also two calendars illustrated with images of the Wright brothers flight experiments.

Vaughan Family Papers (1872-1900, 1969, undated) includes photograph albums containing images of family members from Hertford County, North Carolina. Also included is Uriah Vaughan correspondence (1876-1887) and a photocopy of the 1969 appraisal of Uriah Vaughan Heirs Property in Murfreesboro, North Carolina.

This collection contains two unrelated photograph albums of missionary and Y. M. C. A. related photographs of China. Some of the places captured are Taiyuanfu, Wu Ch'eng, Shanghai, Chin SSu, Tientsin, and Peiping. Note that not all the photographs are dated but each has a caption. The collection is estimated to date between the 1920s and 1930s.

Papers (1889, 1907-1958) consisting of correspondence, diaries, yearbooks, scrapbook, songbook, typescript, travel accounts, photographs, newsletters, etc., related to attendance at Salem Academy and College (1908-1911) in Winston-Salem, North Carolina, and to the work (1917 to 1950) of Protestant Episcopal music missionary Venetia Cox (of Greenville, North Carolina) in China. Also includes letters and school materials related to Lo-I (or Louis) Yin who attended Carleton College in Northfield, Minnesota, from 1949 to 1951 on a scholarship related to Venetia Cox's music missionary work with Huachung University, Wuchang, Hupeh, China.