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Journal of a Cruize in the USS Independence, Commodore William Bainbridge's Flag Ship, Capt. William M. Crane, Commander, from Boston, July 2nd, 1815 (3 July–15 November 1815), compiled by an anonymous crew member, which describes the first overseas mission of the first ship of the line commissioned by the United States Navy, to deal with the piratical acts of the Barbary Powers against American merchant commerce in the Mediterranean Sea, bound in original calf leather over marbled boards, entries clean and legible; also a letter from William M. Crane, Commanding Officer, USS Delaware, Port Mahon (20 September 1829) to Lt. William N, McKean, U.S. sloop Warren, ordering him to report to Lt. Thomas M. Newell, commander of the U.S. schooner Porpoise.

Papers include photocopies of transcriptions of correspondence (1863-1864) written by Josiah Robert Peele Ellis of Wilson Co., North Carolina, to his wife Elizabeth Grimes Ellis while he was serving in Company C of the 43rd N.C. Infantry Regiment during the Civil War. The letters were transcribed in 1977 by Hugh Buckner Johnston who also provided supplementary information. Also included are genealogy records for the Ellis and Hill families of Eastern North Carolina.

The collection includes materials (1898-1959) documenting the work of Shackleford Banks native Josiah Clark Chadwick working on freighters running from North Carolina to New York, and then with the Army Corps of Engineers in North Carolina (1927-1959) working the Eastern N.C. federal waterway projects on diesel engines and then inspecting dredges. Included are family history, Chadwick's work history, training materials, engineers' level books, logbooks, and inventories of engineering property in Chadwick's charge.

Autobiography of Joseph Greene Boyette's life from his childhood (born 1929) upbringing in eastern North Carolina until 1952 when he got out of the U.S. Navy and headed to Duke University to take classes. Boyette actually starts his memoir with some information on the extremely hard upbringing his mother (born 1903) had and also includes a section of notes that his mother wrote about the childhood experiences of her 3 boys.

This collection contains materials of alumnus Margaret Frances Brake from her time as a student at East Carolina College. Many items relate to graduation.

Frances Brake discusses her time as a student at East Carolina College, her family's farming in Edgecombe County, North Carolina, and her teaching career.

Papers (1767-1976) of three generations of Beaufort County, NC, lawyers named William B. Rodman, including correspondence, letterpress books, speeches, financial records, legal files, farm records, clippings, printed material, newspapers, photographs, genealogical material and miscellaneous. Originally from New York, the Rodmans married into the prominent Blount family in Beaufort County, NC. The Rodmans also held local and state government offices and were judges.

Papers (1839-1883, 1930) consisting of correspondence, sermons, notebooks, magazine, newspapers, church conference, reports, writings, theological manuscripts, etc.

Papers (1860-1919, 1943) of John L. Bridgers family of Edgecombe County, North Carolina, including correspondence, photographs of the family home "Hilma," family members, and farm scenes, 1869 tax receipt, and a pardon signed by U.S. President Andrew Johnson.

Collection (1838-1936) including correspondence, Genealogical information, account books, clippings of recipes, Treasurer's book, minute book, etc.

Diaries (1938-1950) of an anonymous Englishwoman written during part of her time as an Anglican missionary in Kenya and Rhodesia. The content of the journals consists primarily of the author's reflections and ideas regarding Christianity. She briefly reflects upon the events of World War II. Also included are to-do lists, logs of her time spent in prayer, and notations regarding travels, and the anniversaries, birthdays, and deaths of friends and family.

The collection contains papers related to Dr. Mabe's personal medical practice, personal papers, product advertisements, and journal.

Papers (1872-1987) consisting of letters, biographical notes, scrapbook, certificates, insurance policies, booklets, bulletins, journals, sermons, etc. of Dr. Neil Graham Bethea (1872-1957), a Methodist Protestant evangelist and minister in North Carolina.

This collection contains the records of the Office of Innovation and Engagement, which pertain to copyright, patents, and intellectual property created by faculty, staff, and students of the university.