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Papers of Stuart Wright (1783-2020, [Bulk: 1945-2014], undated) documenting the life and literary career of the noted Roxboro, North Carolina-born American educator, chiropodist, author, translator, bibliographer, editor, historian, publisher, musician and collector, vendor and donor of literary and musical manuscripts and published materials; consisting of correspondence, holograph and typescript manuscripts of published materials, clippings, loose manuscript items transferred from the Stuart Wright Book Collection; also original art, audio recordings, proofs and advance review copies of published works, photographic materials and oversized materials; including materials in English, French, German, Italian, Latin, Portuguese, Russian and Spanish.

Papers of Andrew Nelson Lytle (1934–1992, undated) documenting the life and literary career of the noted Murfreesboro, Tennessee-born, American biographer, novelist, dramatist, literary critic, educator, and editor, who became a leader and spokesman for the Southern Agrarian literary movement, including correspondence, manuscript materials, typescripts and holographs, printed materials, and loose manuscript items transferred from the Stuart Wright Book Collection.

Papers (1705-1983, undated) including correspondence, diaries, genealogical records, legal and financial records, club records, photographs, clippings, surveys, and miscellaneous.

Major General Charles Justin Bailey was born at Tamaqua, Pennsylvania, on June 21, 1859. He commanded the 81st Infantry Division, American Expeditionary Forces, fighting in France during 1918 and 1919. Bailey compiled this album during 1918 and 1919 and it contains postcards of French and German towns and provinces; a few letters; photographs of France and the 81st Division including behind the lines scenes, Camp Jackson in Columbia, South Carolina, and identified officers and dignitaries; clippings and ephemera; and eight large color fold-out maps. The strength of the collection is its representation of World War I in France.

Papers (1830 – 2010, undated) [Bulk: 1940-1970] documenting the life of Robert Lee Humber, Jr., who was born 30 May 1898 – and died 10 November 1970, in Greenville, North Carolina; after attending local schools he earned a BA from Wake Forest College, 1921; he then attended Oxford University in the United Kingdom as a Rhodes Scholar, 1921-1923; he then earned a MA from Harvard University in 1936; he moved to Paris, France, in 1926, where he married and served as an American Field Service fellow, 1926-1928, and subsequently earned a fortune as an international lawyer, art dealer, and businessman, 1930-1940, until the Fall of France, in 1940, when he, his wife, and their two sons, John and Marcel, fled the German invasion - his infant daughter Eileen died during their escape - and he returned to North Carolina, where he purchased a farm on Davis Island, established a legal career, and devoted himself to public service and to a wide range of philanthropic causes, as an educator, civic, cultural, political and religious leader; beginning in 1940, he became well-known nationally and internationally for establishing and leading the World Federation movement as a way to promote lasting world peace through international law; statewide for persuading the General Assembly and the Kress Foundation of New York to fund and establish the North Carolina Museum which opened in 1956; also as an art collector and patron of local and regional volunteer organizations; as a Democratic state senator from Pitt County, 1958-1964; as an educator who led the effort to create Pitt Technical Institute (later Pitt Community College); as a leader in the Southern Baptist denomination becoming a member of the Board of Trustees of Wake Forest College and other Baptist institutions; and as an attorney and business leader and developer; additionally, the collection includes historical files documenting the history of the World Federation in the United States, compiled by his son, John Leslie Humber.

Collection includes papers related to the personal life and non-university activities of East Carolina University History Professor Lawrence Fay Brewster (ECU professor from 1945 to 1969) for whom the Lawrence F. Brewster Classroom Building on campus was named in 1974. Included are materials (1857-1945) related to his parents and ancestors, Brewster's early life and education through earning his Ph.D., his teaching job at Cranleigh School for Boys in St. Petersburg, Florida, and his work with the Works Progress Administration as Research Editor for the Historical Records Survey of North Carolina. The vast majority (1960-1991) of the collection concerns his work as historiographer for the Episcopal Diocese of East Carolina and writing his "History of the Protestant Episcopal, The Diocese of East Carolina."

Diary compiled (8/19/1943 - 9/15/1945) while serving as a US Navy Electrician's Mate 2/c aboard the USS Essex (CV 9) during World War II, including diagrams of electrical equipment, descriptions of daily life at sea; defending against air and torpedo attacks; attacking the Japanese-held islands of Marcus, Wake, Rabaul, Tarawa, Marshalls (Roi, Kwajalein) Truk, Saipan, Bonin, Guam, Philippines (Mindanao, Luzon, Cebu), Okinawa, Formosa, Indo-China, Tokyo, Iwo Jima, and the Japanese main islands; the naval battles of the Marianas Islands, the Philippines Sea, the Philippines typhoon of 1944, and attacks by kamikazes.

Collection holds medical notebooks from various sources. Two notebooks found in the Laupus Library History Collection with no presently known provenance. One notebook is a dietetics notebook from E. Alexander at General Hospital, Patterson, New Jersey. The other notebook is Dr. Edward Beach Crowell's medical recipe book. An additional notebook was added to the collection in 2018. This notebook, purchased from Palinurus, was the business record for a Connecticut physician in the 1840s. Two more notebooks were added in 2022. They document medical products.

Papers (1907-1921) including correspondence, post cards, photography, a diary, a newspaper, and miscellaneous.

The Jack Minges Papers include photographs, clippings, and memorabilia related to the Minges family's relationship with East Carolina, especially the dedication of Minges Coliseum.

The Beavans Drugstore of Enfield, North Carolina was established in 1901. The papers consist of a blank statement with "W.E. Beavans, Druggist" and a photograph of front of store with William (Willy) E. Beavans.

This collection contains the life history of Lt. Commander Harold Stacey Burdick, who served in the Border War (1910s) and the Tampico Affair (1914), and World War I. It contains letters that he sent to his mother and father and a log journal detailing his accounts while on the USS Jouett. There are also news clippings and pictures of/about Harold Burdick as well as Annapolis and Naval ships like the USS Rhode Island. The collection also contains correspondence between his father, Daniel P. Burdick, and various associations and societies like Brown University, Columbia University and the U.S. Navy.

Letter (1864) from commander of the 67th Regiment N.C. Infantry requesting a father to send his sons back to the regiment.

Letters and ephemera (1926-1929) related to the life of Agnes Wadlington [Barrett], who was born in Trigg County, Kentucky in 1902, before she took a job at East Carolina Teachers College (now East Carolina University) as secretary to the president of the college. Also found with these papers are many photographs of members of the Putnam family of Murray, Kentucky. The only connection between Mrs. Barrett and the Putnam family appears to be that both she and Louise Vey Putnam Carter's husband Herbert Leland Carter both worked at East Carolina University. An 1982 engagement calendar kept by Mrs. Barrett documents her life during retirement in Greenville, North Carolina.

This collection consists of materials and documents (1918-1986) pertaining to the lives and military service of Macon Jasper "Jack" Moye, Sr. and his son, Macon Jasper "Jack" Moye, Jr. Most of the collection pertains to Macon J. Moye, Jr.'s military career (1937-1968), as well as his personal life and teaching career. Macon J. Moye, Jr.'s materials include official documents and correspondence from his career in the U.S. Army, personal correspondence with his wife, photographs, clippings, ephemera, and books and other published material relating to his career and life. Macon J. Moye, Sr.'s materials (1918-1966) consist of official documents, manuals, and correspondence from his service during WWI. His materials also include personal items, like contracts pertaining to his tobacco warehouse and clippings about his life and family.