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The collection includes correspondence, printed materials, photographs, grade reports, teaching certificates and testimonials, legal documents and newspaper clippings which document the life (1891-1975) of Lenoir County, North Carolina, school teacher Julia Catherine McDaniel including her education at Hollins Institute in Virginia and her teaching career (1912-1960) in Burlington, Bethel, and Lenoir County, N.C., schools. The collection also touches on the lives of her friends, classmates, colleagues, and students and includes materials concerning the McDaniel, Harvey, Linton and related families of Kinston and Eastern North Carolina.

Papers (1892-1940, 1960-1964, 1972, 1988) consisting of correspondence, pamphlets, photographs, clippings, newspapers and a book pertaining to the life of Rev. David Wells Herring, a Baptist missionary in China. The book titled Papa Wore No Halo was written about Herring by his daughter Susan Herring Jefferies Taynton.

Papers, 1861-2011 (bulk 1940-1992), undated, of Senator Robert Burren Morgan, an ECU alumnus and lawyer, who served the state of North Carolina in a variety of elected and appointed positions. His first elected position was clerk of court in Harnett County. He was elected to the State Senate, served as president pro tempore of the Senate, and was twice elected Attorney General of North Carolina. He served in this position until 1974, when he won the United States Senate seat vacated by Senator Samuel James "Sam" Ervin, Jr. Morgan served as United States Senator from 1975 to 1981. He returned to his law practice following an unsuccessful reelection campaign and later served as Director of the State Bureau of Investigation from 1985 until 1992. Morgan served as a member of the ECU Board of Trustees for fifteen years, including nine terms as chair in the 1960s. He helped the institution achieve university status and was instrumental in establishing the ECU School of Medicine. The collection includes series relating to Morgan's family and personal matters, North Carolina Senate Files, Attorney General Files, United States Senate Files, North Carolina State Bureau of Investigation Files, and Oversized Materials Files. It includes manuscripts, photographs, audio and video materials, electronic records, printed materials, and ephemera.

This collection contains the records (1872-2014, undated) for the Cumberland Lodge No. 5, Knights of Pythias, in Fayetteville, North Carolina. Types of material included are correspondence, financial records, rosters, visitors' registers, by-laws, deeds, records of proceedings and printed material. Membership information often gives a member's age, dates when each class or rank was attained, date of death and what dues were collected. In some cases indication is also given as to when membership was withdrawn, suspended or reinstated.

Lockey Family Collection (1891 - 2002, undated) relating to the Lockey Family, early settlers of the Pamlico River valley, including the Will of Joseph Lockey, 30 January 1746, copied from the NC Historical Commission, NC Wills, Vol. XVIII, p. 54-56 (Mss typescript); "In Memoriam of J. P. [John Peyton] Lockey (1805-1891) (Photocopy); Letter from Mrs. Donald A. Philbrick, 21 Oakhurst Road, Cape Elizabeth, ME, undated to "Dear Cousin Peyton" regarding Lockey family genealogy (Photocopy typescript); Letter from "Daddy," Tallahassee, FL, 7 September 1953, to "Dear Hope," regarding John Peyton Lockey (Photocopy typescript); and Letter from Jon Guy Diffenbaugh, Greenville, NC 3 May 2002, "To whom it may concern," transmitting the collection.

Correspondence (1910-1911, 1913-1914) between Belva Agnes Ross and her parents William Henry Ross and Lida Baynor Little Ross and her brother Wilbur "Buddy" Ross while she is attending East Carolina Teachers Training School in Greenville, North Carolina. Wilbur Ross also started attending ECTTS with his sister in October 1910, but at some point he left to attend Guilford College. The Rosses were from Edward community about three miles east of Aurora in Beaufort County, North Carolina. Belva had to withdraw from school in January 1911 because she contracted the measles, but she returned to school at least by October 1913. Also included are abstracts of the correspondence created by Belva Ross's grandson Roy A. Archbell, Jr.

The William Cobb Whitfield Papers consists of a class notebook, ephemera found in books belonging to Whitfield, and various other papers ranging from 1873 to 1936. Additionally, notes from a conversation between Miles J. Smith, donor of collection and great-nephew of Whitfield, and Ruth Moskop, from History Collections at Laupus Library.

This collection contains the records (1873-2010) of the fraternal secret society Knights of Pythias Grand Lodge, Domain of North Carolina. Records include biennial and annual reports of local lodges, the Records of Proceedings for the annual sessions of the Grand Lodge, financial records, minute book, constitutions and bylaws, publications and items such as the 1909 Pythian Service Book.

The bulk of the Raymond J. Kragness Papers (1943-1946, 2000, 2004) pertains to Mr. Kragness's service in the U.S. Navy in the Pacific Theatre in World War II aboard the USS Escambia. Personal items include rites of passage membership cards (such as crossing the Equator), draft board notification, photographs, post cards of San Francisco Bay, course certificates, separation from service records and a brief family history. The remaining items pertain to his service on the USS Escambia, a fleet oiler. Included are the ship's history and directory, newsletter "Eighty Times," a list of ships fuled by the USS Escambia, plans of the day, congratulatory messages from Admiral Halsey, and invitations and tickets for commissioning and decommissioning ceremonies.

Papers (1791, 1846-1941) including correspondence, diaries, visitation books, account books, memoranda books, financial papers, minute books, photographs, land records and miscellaneous.

Collection of papers 1941-2005, undated (bulk 1943-1946), consisting primarily of letters from Pvt. Leon W. Jackson to his sister Lois (Claude E.) Dees and to her son Tony while he was serving in the U. S. Army in Georgia and Europe; also letters from Leon W. Jackson's friend, Pfc. Jerrold S. Robinson to Lois (Mrs. Claude E.) Dees and Leon W. Jackson; also dated photograph and album.

Collection (1947-1951, undated) of programs relating to various organizations at Greenville High School, Greenville, NC. Organizations include the glee club, Dramateers and the football team.

Collection holds medical notebooks from various sources. Two notebooks found in the Laupus Library History Collection with no presently known provenance. One notebook is a dietetics notebook from E. Alexander at General Hospital, Patterson, New Jersey. The other notebook is Dr. Edward Beach Crowell's medical recipe book. An additional notebook was added to the collection in 2018. This notebook, purchased from Palinurus, was the business record for a Connecticut physician in the 1840s. Two more notebooks were added in 2022. They document medical products.

The collection includes notes, hospital nursing manuals, and informational booklets and pamphlets about various diseases and their treatment. The papers belonged to Helen Marion while she was a student nurse in New Jersey in the mid-1950s.

Records (1973-2015) of the North American Society for Oceanic History (NASOH) including correspondence, membership lists, annual conference materials, book awards, bibliographies, newsletters, treasurer's records, programs, and publications.