Dr. Edmund Burke Haywood was born 13 January 1825 to John and Eliza Eagles Asaph (Williams) Haywood. He graduated from the University of Pennsylvania School of Medicine in 1849. The following year, Haywood married Lucy Ann Williams, and they had Edmund Burke, Alfred William, Hubert, Eliza Eagles (Bridgers), Ernest, Edgar, John, Eugene, and Carolina Frances. Haywood established the first North Carolina military hospital during the Civil War; after the war, he worked at Pettigrew Hospital in Raleigh and was elected the President of the Medical Society of North Carolina in 1869. He was the first to perform a number of surgical procedures in the state and country. He died 18 January 1894.

Dr. Hubert Haywood was born 13 May 1855 to Edmund Burke and Lucy Ann (Williams) Haywood. He graduated from Bellevue Medical School in New York. In 1881 Haywood married Emily Ryan Benbury and they had Harriet (Syme), Emily Benbury (McIver), Edmund Burke, John Benbury, and Hubert Benbury. Haywood served as an obstetrician and consulted on typhoid and other fevers. He later became a partner in his father's medical practice as well as the Surgeon General of the North Carolina National Guard and Physician to the North Carolina State School for the Blind. Haywood died 9 August 1927.