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The Herman H. Duncan Collection consists of seven photographic prints (1921–1922, undated) depicting Greenville High School athletic teams and unidentified baseball teams in eastern North Carolina. Included are group portraits of the football, basketball, track and field, and baseball teams from Greenville High School, as well as images of unidentified teams, one possibly from New Bern, North Carolina. The photographs document early 20th-century high school athletics and local sports culture in Pitt County and surrounding areas.

Papers (1934-1969) of N.C. State Senator and U.S. District Court Judge John Davis Larkins, Jr., including correspondence, speeches, judge's notes, case files, clippings, photographs, leaflets, scrapbooks, concerns of state fishery industry, information of osteopathic profession, etc.

Papers (1942-1947) include correspondence related to the World War II U.S. Navy careers of Frank A. Bartimo and his brother-in-law Richard Toomey, and Bartimo's civilian life with the Army's Judge Advocate section stationed in post-war Heidelberg, Germany.

Includes medical school class notes, medical licenses, patient notes, account books, certificates, diplomas, and photographs.

Includes minutes of meetings of the college faculty and meeting minutes and correspondence of faculty sub-committees.

This collection contains about 363 cubic feet of material documenting the Congressional career of Lunsford Richardson Preyer. Mr. Preyer (January 11, 1919-April 3, 2001) of Greensboro, North Carolina, served in the U.S. House of Representatives for twelve years (January 1969-January 1981).

Records (1930-1967) of the firm of James W. Griffith, Jr., Architects, Greenville, NC, including drawings and other records.

Collection of photographic materials dating from 1944 to 1974 created by Dr. Samuel T. White, II, a Greenville, North Carolina optometrist. Materials include photographic prints, negatives, slides, indexes, and printed forms documenting personal, professional, and artistic photography. Subjects include portraits of family and acquaintances as well as landscape and community scenes primarily depicting Eastern North Carolina. An additional group of forty five black and white photographic prints is also included.

Papers include daily and monthly reports; trial statements; criminal investigation procedures; policies; training publications and the quizzers that accompanies them; certificates; commendation; newspaper and article clippings; photographs; negatives; brochures; flyers; signs; correspondence: two sets of notes of screenplay research on Garland Bunting; Kopka's retirement speech; sketch; armband; and a roster that lists violators.

Papers (1943-1946) including correspondence, post cards and a poem.

Papers (1947-1960) including correspondence, references concern Bible, auditing of books, school events, receipts, pilgrims, and miscellaneous.

Papers of physician C.H. Brantley (1860 – 1942). The papers consist mainly of a medical school photograph with cadaver and prescription slips.

Papers (1890-1914, 1948, 1982) including correspondence, organizational publications, newspaper clippings, advertisements, blueprints, a contract, and miscellany.

Papers (1907-1921) including correspondence, post cards, photography, a diary, a newspaper, and miscellaneous.

Collection (1901-1926) of correspondence received by Maud Smith (née Tyson) and her husband Walter Edward "Edd" Smith, from family and friends. Collection includes letters to Maud Tyson, while she attended Littleton Female College, letters from Carl Tyson, during World War I, from the Headquarters of the 81st Division, at Camp Jackson, South Carolina, between May and November, 1918, and several other letters, as well as a list of transcripts and typed transcripts of all letters in the collection.