Indigenous tobacco plants satisfied early settlers' appetites but in 1852 the first \"bright leaf\" tobacco was grown and started the state's tobacco boom. The popularity of J. L. Green's tobacco with Civil War soldiers created the world-famous \"Bull Durham\" brand. The Duke's became prolific tobacco farmers and the \"Duke's Mixture\" helped J. B. Duke form the American Tobacco Company. The tobacco industry was not limited to the 'Triangle' and places like Winston-Salem became cigarette manufacturing locales.