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| S.S. ZamZam Collection #0906 |
| Sager, Frederick N., Papers #0677-020 |
 | Salisbury, Frank C., Collection #0099 |
| Sanborn Maps of Greenville #MC0010 |
| Sanders, Aggie Hodge, Papers #0314 |
| Sanderson Family Collection #0883 |
| Sandra Hunsucker Oral History Interview #OH0223 |
| Sandy Bottom Primitive Baptist Church Records #CR0007 |
| Sanger, Frank M., Jr., Oral History Interview #OH0093 |
| Sans Souci Book Club Records #0436 |
 | Saunders Family Collection #0964 |
| Savage, Elizabeth Evans, Oral History Interview #OH0085 |
 | Scales, Alfred M., Papers #0048 |
| Schack, William A., Oral History Interview #OH0024-053 |
| Schenck, Nicholas W., Journal #0342 |
| Schild, Jean, Papers #0677-055 |
 | Schlobin Literature of the Fantastic, James H. and Virginia, Collection #1029 |
| Schoenbaum, Howard R., Oral History Interview #OH0130 |
| Schreier, Robert L., Oral History Interview #OH0105 |
| Schroll, Daniel, Oral History Interview #OH0024-014 |
| Schweizer, Jack R., Papers #0564-006 |
| Scott, Ralph L., Collection #0909 |
| Seabrook, Arch F., Papers #0677-003 |
 | Seawell, Herbert Floyd, Jr., Papers #0496 |
 | Seawell, Herbert Floyd, Sr., Papers #0497 |
| Seedlock, Walter F., Papers #0622 |
| Seedlock, Walter, Oral History Interview #OH0133 |
 | September 11, 2001 Collection #0885 |
| Settle, Fay Brackett, Oral History Interview #OH0081 |
| Sexauer, Donald, Papers of #UA90-03 |
| Shaver, Kenneth David, Sr., Oral History Interview #OH0136 |
 | Shaw, Leslie Avery, Papers #0992 |
| Shaw-Robinson Family Papers #0092 |
| Sheaffer, William T., Papers #0671 |
| Sheep, Samuel Lloyd, Papers #0233 |
| Sheffer, Ralph, Oral History Interview #OH0024-029 |
| Shefveland, Stan, Oral History Interview #OH0024-035 |
| Shelly, Tully, Jr., Oral History Interview #OH0163 |
| Shepard, William B., Papers #0448 |
| Shepherd, James E., Papers #0199 |
| Sheppard Family Bible Records #MG0051 |
| Sherrod Tison (Tyson) Bible Records #MG0056 |
| Sherrod, Ethel Clements, Collection #0977 |
| Ship Trafalgar Collection #1063 |
| Shires, William A., Papers #0769 |
| Shotwell, Joyce M., Collection #0882 |
| Shriner Family Genealogy #MG0052 |
 | Shuping, Clarence Leroy, Papers #0553 |
| Sierra Club, North Carolina Chapter Records #0776 |
| Sigma Tau Delta: The Rectangle #UA50-31 |
| Sills Family Ledgers #MF0011 |
| Sills Family Papers #0201 |
| Sills, Louise J., Oral History Interview #OH0004 |
| Silverman, Milton J., Oral History Interview #OH0154 |
| Simeon O. Holloway Oral History Interview #OH0215 |
| Simmons Patterson, Dr. F.M., Papers of #UA90-18 |
| Simmons, Furnifold McLendel, Collection #0965 |
| Simpson, Carter Berkeley, Papers #0646 |
| Singletary, George B., Singletary Chapter U.D.C. Papers #0108 |
| Sink, Robert Frederick, Papers #0255 |
| Sisco, Herbert L., Oral History Interview #OH0024-015 |
| Skewarkey Primitive Baptist Church Union Records #1015 |
| Skewarky Union Meeting Records #MF0030 |
| Skipper, Jay, Oral History Interview #OH0024-026 |
| Skrzynski, Walter E., Papers #0677-028 |
| Slack, William Bond, Papers #0717 |
| Sloan, W. G., Collection #0969 |
| Sloop Agnes Collection #0843 |
| Small, Walter L., Jr., Oral History Interview #OH0158 |
 | Small, Walter L., Jr., Papers #0731 |
| Smallwood, Arwin D., Papers #1070 |
| Smiley, Wendell, Papers of #UA90-17 |
| Smith - Tyson Family Collection #1118 |
| Smith Island North Carolina Map #MC0001-004 |
 | Smith, Albert R., Collection #0009 |
| Smith, Charles W., Jr., Collection #0228 |
| Smith, Charles, Papers #0677-032 |
| Smith, Ephraigm H., Collection #0145 |
| Smith, Essie T., Collection #0174 |
| Smith, Harold A., Oral History Interview #OH0024-045 |
| Smith, Irwin S., Oral History Interview #OH0074 |
| Smith, Joseph J., Papers #0677-022 |
| Smith, L. H., Papers #0023 |
| Smith, McNeill, Papers #0373 |
| Smith, Nancy Joyner, Papers #1165 |
| Smith, Richard Hamilton, Papers #1171 |
| Smith, Sallie Phillips, Oral History Interview #OH0011 |
 | Smith-Grady Family Papers #0094 |
| Smith-Skinner Family Collection #0815 |
 | Snow, Benjamin Galen, Papers #0740 |
| Snyder, Donald D., Jr., Oral History Interview #OH0117 |
| Society of Colonial Wars in the State of North Carolina #0859 |
| Society of the Antiquaries of Scotland Collection #0892 |
| Somers, Francis Eugene, Oral History Interview #OH0109 |
| Sons of the Revolution in the State of North Carolina Records #0715 |
| Soutern States Railroad and County Map #MC0039 |
| South Atlantic Philosophy of Education Society Records #0451 |
| Southard, Pemberton, Oral History Interview #OH0199 |
| Southard, Pemberton, Papers #0551 |
| Southern Railway Company Papers #0028 |
 | Spain, Jack Holland, Papers #1122 |
| Sparrow, Dr. Keats, Collection #0854 |
 | Sparrow, Thomas, Papers #0001 |
 | Sparrow, W. Keats, Papers #0013 |
| Sparta Alliance No. 218 Minute Book #0560 |
| Speight, Henry F., Collection #1047 |
| Speight, Robert Ann Rhodes, Memoir #0515 |
| Speight, Robert H., Papers #0106 |
 | Speir, Betty, Papers #0386 |
| Spilman, J. B., Collection #1020 |
| Spilman, Johnetta Webb, Oral History Interview #OH0012 |
| Spilman, Johnetta Webb, Papers #0097 |
| Spirit of the Ages: Raleigh, N.C. #MN0011 |
| Spitler, Joseph C., Oral History Interview #OH0125 |
 | Spoon, William L., Papers #0170 |
| Spoor, Oliver C., Papers #0308 |
| Spore, Burns W., Oral History Interview #OH0201 |
| Sprague, Frank J., Papers #0628 |
| Spruill Family Papers #0337 |
 | Spry, Jim Will, Papers #0677-082 |
| Spurr, Robert Allen, Papers #0677-033 |
| SS HAGOOD Collection #1034 |
 | SS RINGLEADER Collection #1090 |
| St. Amand, Jeannette Cox, Collection #0349 |
| St. Barnabas Episcopal Church Records #1026 |
| St. James African Methodist Episcopal Zion Church Collection #1078 |
| St. John, Andrew Warner, Papers #0320 |
| St. Paul's Episcopal Church #MF0044 |
| St. Paul's Episcopal Church Papers #CR0004 |
| St. Thomas Episcopal Church Collection #0987 |
| St. Thomas' Episcopal Church Records #1039 |
| Stallings, George B. H., Jr., Papers #0735 |
| Stallings, Mary Earle, Collection #0935 |
 | Stallings, Rufus Delano, Papers #1141 |
| Stancill, Mae Tucker, Collection #1065 |
| Stanley Family Papers #0573 |
| Stanley, Abigail Brothers, Memoir #0243 |
| Star Brick Warehouse Records #0504 |
| Starkey, Marshal L. and Rebecca, Collection #0787 |
| Starling, Alton H. "Bill", Oral History Interview #OH0024-016 |
| Stars and Stripes, the: France #MN0007 |
| Stasavich, Clarence, Papers of #UA90-07 |
| State of North Carolina #MC0001-005 |
| Stauderman, Philip, Papers #0677-001 |
| Steamer Olive Collection #1050 |
| Steele, Ralph H., Papers of #UA90-01 |
| Steelman, Dr. Lala Carr, Collection #0827 |
 | Steelman, Joseph F. & Lala Carr, Papers #0924 |
| Steelman, Joseph F., Papers #0774 |
| Stenhouse, Dr. Henry, Oral History Interview #OH0089-015 |
| Stenhouse, Henry Merritt, Oral History Interview #OH0060 |
| Stenhouse, Henry Merritt, Papers #0401 |
 | Stephenson, E. Frank, Jr., Collection #0692 |
| Sterrett, Charles S., Collection #0978 |
| Stevens, David B., Oral History Interview #OH0263 |
| Stevens, David B., Papers #0779 |
| Steward's Weekly Provisions Register #0732 |
| Stewart, Richard W., Oral History Interview #OH0188 |
| Stewart, Vance, Papers #0695 |
 | Stewart, William E. and Marion B., Papers #0707 |
| Sthreshley, Charles A. & Sthreshley, Florence M., Oral History Interview #OH0073 |
 | Still, William N., Jr., Papers #0139 |
| Stokes, Kathleen E., Papers #0947 |
| Stokes, Richard C., Papers #0402 |
| Stokes-Collins Family Genealogy #MG0053 |
| Stone Towing Line Records, #0679 |
| Stone, D. W., Journal #MF0004 |
| Stone, Gloria Sutton, Collection #0556 |
| Stone, Guy P., Papers #0697 |
| Stone, James B., Papers #0760 |
| Strickland--Harper Bible Records #MG0054 |
| Stroud, William Emmette, Sr., Collection #1105 |
| Strum, Charles Gray, Oral History Interview #OH0106 |
| Strum, Charles Gray, Oral History Interview #OH0208 |
| Stryker, Joe W., Oral History Interview #OH0053 |
| Stryker, Joe Warren, Papers #0339 |
| Stryker, Joe, Oral History Interview #OH0024-061 |
| Stubbins, Roland Clinton, Papers #0116 |
| Stubbs, Harry Williams, IV, Collection #1072 |
| Student Government Association, Records of #UA22-01 |
| Student Handbooks #UA50-04 |
| Student Oral Histories #UA45-05 |
| Styer, Charles W., Jr., Oral History Interview #OH0145 |
| Styron, William Papers #1169-011 |
| Sugg Family Collection #MF0039 |
| Sugg, B. B., Papers #0219 |
| Sugg, H. A. I., Oral History Interview #OH0040 |
| Sugg, H. A. I., Papers #0764 |
| Sugg, Harold G., Papers #0494 |
| Summerville, Don L., Oral History Interview #OH0180 |
| Sutton Family Collection #1205 |
| Sutton Family Papers #0315 |
 | Sutton, Fred I., Papers #0706 |
| Sutton, William F. and Cora, Bible Records #MG0055 |
| Svendsen, Edward C., Oral History Interview #OH0113 |
| Svendsen, Edward C., Papers #0574 |
| Sweet, Carroll F, Jr., Papers #0564-012 |
| Swift, Ralph, Oral History Interview #OH0024-027 |
| Szabo, Joseph, Papers #0677-069 |