Bedford Brown was born January 17, 1825, in Caswell County. He studied medicine at Transylvania University in Lexington, Kentucky, and spent several years in Virginia building a fine reputation as a physician before moving back to Yanceyville. In 1861, he became chief surgeon for the Confederate States training camp at Weldon and was appointed inspector of hospitals and camps in the Confederate Army. After the Civil War, he returned to Alexandria, Virginia, where he was a distinguished member of the Southern Surgical and Gynecological Association, as well as a member of the Virginia Board of Medical Examiners. Throughout his career he wrote several papers on disease and used his own techniques to work on healing diphtheria, meningitis, pneumonia, and other diseases. In 1896, he was elected president of the Virginia Medical Society. He died a year later at his home in Virginia.