Best Doctors, Inc. is a Boston-based company that offers one way to rate physicians. The company asks about 35,000 physicians and surgeons nationwide to grade other doctors in their specialty. Those with the highest averages make the final list. In the state, about 5 percent, or 889 doctors made the list. Business North Carolina lists doctors in the state who made the list in twenty-one specialties, including cardiovascular, infectious disease, nephrology, and ophthalmology.